Interstitial Cystitis: Diagnostic Tests

Obligatory medical device diagnostics.

  • Urethrocystoscopy (urethrocystoscopy) with hydrodistension (overdistension of the urinary bladder) – Under anesthesia, the urinary bladder is dilated with isotonic saline. The overdistension can reveal characteristic glomerulations (pinhead-sized hemorrhages in the bladder wall) as well as mucosal tears (“mucosa cracking”). To rule out carcinoma in situ, a biopsy (tissue sample) is usually performed. Caveat: In the early stages of IC is not yet detectable tissue changes.If necessary, also conduct a potassium chloride test: predictor GAG therapy (due toGAG therapy see below Drug therapy).

Optional medical device diagnostics – depending on the results of the history, physical examination, laboratory diagnostics, etc. – for differential diagnostic clarification.

  • Magnetic resonance (MR) urography – if complex malformations of the kidney are suspected; if necessary, also to assess renal function, drainage ratios, and scarring in the renal parenchyma
  • Micturition cystourethrography (MZU; examination method in which the urinary bladder and the urethra before and during micturition with the help of contrast medium in the context of an X-ray examination are represented) or sonographically as micturition sonography (MUS) – to exclude or detect a vesicoureteral reflux (VUR; unphysiological reflux of urine from the bladder via the ureters (ureters) into the renal pelvis).
  • Renal ultrasonography (ultrasound examination of the kidneys) including the draining urinary tract – if pyelonephritis (inflammation of the renal pelvis) is suspected to exclude complicating factors.
  • Rectal prostate ultrasonography – when prostatitis (prostatitis) is suspected.
  • Uroflowmetry (urine flow measurement) – in chronic cystitis to detect or exclude urinary bladder emptying disorders.
  • Urosonography – assessment of the morphology of the urogenital tract/urinary and sexual apparatus.
  • Cystometry (bladder pressure measurement) – in chronic cystitis to detect or exclude urinary bladder emptying disorders.