Liver Shrinkage (Cirrhosis): Therapy

General measures

  • Alcohol abstinence (complete abstinence from alcohol).
  • Nicotine restriction (refrain from tobacco use) including passive smoking – smoking promotes fibrosis of the liver.
  • Review of permanent medication due topossible effect on the existing disease.
  • Avoidance of environmental stress:
    • Arsenic
    • Formaldehyde
    • Carbon tetrachloride

Vaccinations

The following vaccinations are advised, as infection can often lead to worsening of the present disease:

  • Flu vaccination
  • Hepatitis A vaccination
  • Hepatitis B vaccination
  • Pneumococcal vaccination: immunocompromised individuals should be vaccinated sequentially with the 13-valent conjugate vaccine PCV13 and six to 12 months later with the 23-valent polysaccharide vaccine PPSV23 against pneumococcus.

Regular checkups

  • Regular medical checkups

Nutritional medicine

  • Nutritional counseling based on nutritional analysis
  • Nutritional recommendations according to a mixed diet taking into account the disease at hand. This means, among other things:
    • A total of 5 servings of fresh vegetables and fruit daily (≥ 400 g; 3 servings of vegetables and 2 servings of fruit).
    • Once or twice a week fresh sea fish, i.e. fatty marine fish (omega-3 fatty acids) such as salmon, herring, mackerel.
    • High-fiber diet (whole grains, vegetables).
  • Observance of the following special dietary recommendations:
    • Wg. malnutrition: in cirrhosis of the liver, especially the energy and protein (protein) intake is usually insufficient due to a decreased appetite and impaired sense of taste. Often, a feeling of satiety sets in quickly. The recommended daily energy intake should be 35-40 kcal per kilogram of body weight (with a protein content of 1.2 g/kg, in severe malnutrition 1.5 g/kg protein per day) and adapted to physical activity.
    • Dietary salt restriction in patients with liver cirrhosis and ascites (abdominal fluid) [S2k guideline: see below]:
      • At least patients with refractory and difficult-to-treat ascites should take a maximum of 5 g sodium chloride (85 mmol sodium) daily
      • In cases of marked hyponatremia (sodium deficiency; < 125 mmol/l): fluid restriction to 1.5 liters/day
    • Most often, glycogen reserves (reserves of stored carbohydrates) are decreased, so hypoglycemia (low blood sugar) may occur in liver cirrhosis. If hypoglycemia is imminent, carbohydrates with a high glycemic index (e.g., white flour products, glucose) are helpful because they are quickly available to the organism. Otherwise, complex carbohydrates should preferably be consumed in small distributed meals. Carbohydrate-rich late meals are also recommended, because it can also come at night to hypoglycemia.
  • Selection of suitable food based on the nutritional analysis.
  • See also under “Therapy with micronutrients (vital substances)” – if necessary, taking a suitable dietary supplement.
  • Detailed information on nutritional medicine you will receive from us.