Products
Lysine is commercially available as a monopreparation from Burgerstein, among others, in the form of tablets.
Structure and properties
Lysine (C6H14N2O2, Mr = 146.2 g/mol) is a natural and essential amino acid found in proteins and, for example, in meat. Essential means that the body must take it in with food and does not produce it itself. Lysine carries a basic primary amino group at the end of the side chain, which is protonated at physiological pH (NH3+). It is often present in products as lysine hydrochloride, a white crystalline powder that is readily soluble in water.
Effects
Lysine (ATC B05XB03) is a natural protein component and thus involved in numerous bodily functions. It is a precursor of acetyl-CoA and carnitine. Bacterial degradation (putrefaction) of lysine leads to cadaverine. The antiviral effects are attributed to lysine being an antagonist of arginine, which is required for viral replication. Small clinical studies have been conducted showing that cold sores are less common while taking it. However, whether it is actually effective has not been conclusively proven (Chi et al. 2015).
Indications for use
To prevent the recurrence of cold sores or other herpes virus infections (eg, genital herpes).
Dosage
According to the directions for use. The 500 mg tablets are usually taken once or twice daily. In the literature, a dose of 1000 mg daily is recommended for prevention.
Contraindications
- Hypersensitivity
- Hyperlysinemia
We do not have a complete list of precautions.
Adverse effects
No complete information is available. However, lysine appears to be well tolerated at the doses used.
