Laboratory parameters of 1st order – obligatory laboratory tests.
- Culture of the pathogens from a smear of the ulcer.
- Special staining (Gram preparation), with which the pathogens become visible under the microscope [pathognomonic for H. ducreyi are fish-train-like structures].
- Culture
- Nucleic acid amplification test (NAAT) – very high sensitivity and usually more sensitive than classical microbiological methods (culture, microscopy) [method of choice].
Laboratory parameters 2nd order – depending on the results of the medical history, physical examination, etc. – for differential diagnostic clarification.
- Bacteria
- Chlamydia trachomatis (lymphogranuloma venereum) – serology: Chlamydia trachomatis.
- Neisseria gonorrhoeae (gonorrhea, gonorrhea) – genital swab for pathogen and resistance, specifically for Neisseria gonorrhoeae.
- Treponema pallidum (syphilis, lues) – antibodies against Treponema pallidum (TPHA, VDRL, etc.); Ureaplasma urealyticum.
- Viruses
- HIV (AIDS)
- Herpes simplex virus type 1/2 (HSV type 1 u. 2)
- Human papilloma virus [HPV] (Condylomata acuminata)
- Fungi/Parasites
- Fungi: Candida albicans and others Candida species genital swab – pathogen and resistance).
- Trichomonas vaginalis (trichomoniasis, colpitis) – antigen detection.
