Mycosis Fungoides: Symptoms, Complaints, Signs

The following symptoms and complaints may indicate mycosis fungoides (stage-dependent):

Stage I: Premycous stage (eczema stage).

  • Uncharacteristic skin rashes, such as large-heart parapsoriasis (psoriasis) or eczema (skin inflammation; “itchy rash”)
  • Yellowish-brownish non-infiltrated foci
  • Efflorescences (visible skin changes) may disappear and reappear in other locations. However, they may also persist (persist).
  • Pruritus (itching)

Predilection sites (body regions where the disease occurs preferentially) for the skin changes are initially upper arm and inner thighs and buttocks.

Stage II: Infiltrative stage (plaque stage).

  • Infiltration of the foci with palpable thickening of the skin (flat raised).
  • The foci are brown-red and vary in size, sometimes anular (ring-shaped).
  • Larger plaques (elevating above the skin level, “plate-like” substance proliferation of the skin) and small nodules.
  • The entire outer skin is affected.
  • Severe pruritus (itching).
  • Lymphadenopathy (enlarged lymph nodes)

Stage III: Mycosidic tumor stage.

  • Formation of hemispherical, mushroom-shaped tumors within infiltrates with tendency to erosions (skin defects) and ulcerations (boils)
  • Often the face is also affected (“Facies leonina” = lion face).
  • In severe courses it comes to erythroderma (redness (erythema) of the entire skin organ).

Stage IV: Systemic spread (advanced tumor stage).