Products
Nelarabine is commercially available as a solution for injection (Atriance). It has been approved in many countries since 2007.
Structure and properties
Nelarabine (C11H15N5O5, Mr = 297.3 g/mol) is a purine analog.
Effects
Nelarabine (ATC L01BB07) has cytotoxic properties. The effects are due to inhibition of DNA synthesis.
Indications
Treatment of patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.