Nelarabine

Products

Nelarabine is commercially available as a solution for injection (Atriance). It has been approved in many countries since 2007.

Structure and properties

Nelarabine (C11H15N5O5, Mr = 297.3 g/mol) is a purine analog.

Effects

Nelarabine (ATC L01BB07) has cytotoxic properties. The effects are due to inhibition of DNA synthesis.

Indications

Treatment of patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma.