Pathological Breast Milk Discharge (Galactorrhea): Symptoms, Complaints, Signs

The following symptoms and complaints may indicate galactorrhea (abnormal breast milk discharge):

Leading symptom

  • Galactorrhea (spontaneous secretion of milk from the breast).

Classification of galactorrhea

Grade Description
I Only a few drops expressible (squeezable)
II At least 1 ml of liquid expressible
III Spontaneous milk secretion at times
IV Constant discharge of milk flow

In younger patients with bilateral secretion (mammillary secretion), physiological galactorrhea is usually present.

Warning signs (red flags)

  • Woman + period disturbance (disturbance of the rhythm of menstruation):
    • Oligomenorrhea (the interval between bleeding is > 35 days and ≤ 90 days, i.e., bleeding occurs too infrequently).
    • Amenorrhea (no menstrual bleeding until 15 years of age (primary amenorrhea) or no menstrual bleeding for more than three months (secondary amenorrhea))

    → think of: Hyperprolactinemia (abnormal prolactin elevation); prolactinoma (possibly also visual disturbances, nausea (nausea)/vomiting).

  • Woman > 50 years + new onset galactorrhea → think of: malignant neoplasm.
  • Purulent secretion → think of: Mastitis (inflammation of the mammary glands) or an abscess (encapsulated collection of pus).
  • Green or brownish secretion → think of: Ductasia (dilated, congested milk ducts) or fibrocystic mastopathy (benign changes in the mammary gland).
  • Hemorrhagic (bloody) galactorrhea: unilateral and spontaneous bloody, serous or watery secretion → think of:
    • Papilloma (relatively common benign epithelial tumor).
    • More rarely also: ductal carcinoma in situ (DCIS) or Paget’s disease of the nipple (form of malignant neoplasia (malignant neoplasm) of the mamma (breast));
    • Postmenopausal women → think of: Mammary carcinoma (breast cancer).
    • Note: > 90% of cases of hemorrhagic galactorrhea have a benign (benign) cause
  • Man + galactorrhea → medical clarification required! (Exception: pubescent boy)