The following are the most important diseases or complications that can be caused by diabetic polyneuropathy, for example:
Endocrine, nutritional, and metabolic diseases (E00-E90).
- Severe hypoglycemia (hypoglycemia) due to lack of awareness of symptoms.
- Diabetic foot or diabetic foot syndrome (DFS) – ulcerations (ulcers) on the feet due to circulatory disturbances of the limb and / or the reduced sensation of pain.
Infectious and parasitic diseases (A00-B99).
- Diabetic diarrhea (diarrhea).
- Infections of the skin ulcers (skin ulcers), which can lead to the need to amputate the affected limb due to poor wound healing
Skin and subcutaneous (L00-L99).
- Chronic ulceration (ulceration; typical localization: sole of foot and big toe; neuropathic ulcus pedis, the so-called malum perforans).
Cardiovascular system (I00-I99).
- Apoplexy (stroke)
- Myocardial infarction (heart attack)
- Orthostatic hypotension (low blood pressure).
Mouth, esophagus (food pipe), stomach, and intestines (K00-K67; K90-K93).
- Gastroparesis – loss of tone of the stomach muscles.
Musculoskeletal system and connective tissue (M00-M99).
- Osteomyelitis – bone inflammation due to deep skin and soft tissue infections.
Psyche – nervous system (F00-F99; G00-G99).
- Diabetic amyotrophy (usually unilateral (one-sided) upper lumbosacral plexopathy, LSP; pain syndrome).
- Cranial nerve palsies (cranial nerve palsies):
- III oculomotor nerve (eye movement nerve); type: motor; function: eye and eyelid movement; adaptation to distance.
- IV trochlear nerve; type: motor; function: superior oblique eye muscle.
- VII facial nerve (facial nerve); type: sensory/motor; function: sensory: anterior part of tongue motor: facial mimic muscles
- Mononeuritis multiplex – inflammatory disease of the nervous system.
Genitourinary system (kidneys, urinary tract – reproductive organs) (N00-N99).
- Bladder atony (flaccidity of the bladder muscles).
- Erectile dysfunction (ED; erectile dysfunction).
Symptoms and abnormal clinical and laboratory findings not elsewhere classified (R00-R99).
- Tachycardia (heartbeat too fast: > 100 beats per minute).
Further
- Decrease in sweat secretion
- Impairment of mitochondrial metabolism.
- Lack of respiratory variability of heart rate.
- Disturbances of the microcirculation
- Unnoticed burns due to lack of sensitivity.
- Non-traumatic leg amputation.