Products
Resorcinol (resorcinol) is present in a few liquid and semisolid drugs. It is also used in the preparation of extemporaneous preparations, but is controversial because of its adverse effects.
Structure and properties
Resorcinol (C6H6O2, Mr = 110.1 g/mol) exists as a crystalline powder or as colorless to faint grayish-pink crystals with a sweetish odor. In air and light, the color changes to red. Resorcinol is very soluble in water. Resorcinol belongs to the phenols and dihydroxybenzenes. Two hydroxy groups are attached to the benzene ring in the m-position (1,3-dihydroxybenzene). The melting point is about 110 °C. Like phenol, resorcinol is slightly acidic.
Effects
Resorcinol (ATC D10AX02, ATC S01AX06) has keratolytic, antiseptic, and mildly corrosive properties.
Indications for use
Medicinal uses include:
- Acne, skin care
- Warts, corns, calluses
Dosage
According to the professional information. The drugs are used exclusively externally on the skin. They must not be ingested or overdosed.
Contraindications
- Hypersensitivity
- Open wounds
- Contact with the eyes
- Children, pregnancy, lactation
- Large area application
Full precautions can be found in the drug label.
Adverse effects
Possible adverse effects include local skin reactions. Absorption of high doses into the skin may cause tissue necrosis and systemic toxicity (e.g., inhibition of thyroid function). Contact with the eyes should be avoided because resorcinol can cause conjunctivitis or corneal inflammation. Finally, resorcinol has photosensitizing properties and mutagenic effects have been shown in animal studies.