Bumetanide

Products

Bumetanide was commercially available in tablet form (Burinex, off label). It was approved in many countries in 1974.

Structure and properties

Bumetanide (C17H20N2O5S, Mr = 364.4 g/mol) is a white crystalline powder that is practically insoluble in water.

Effects

Bumetanide (ATC C03CA02) is diuretic with rapid onset and short duration of action.

Indications

Oedema associated with congestive heart failure and liver cirrhosis (ascites), oedema associated with renal disease including nephrosis syndrome, drug-induced forced diuresis.