Obligatory medical device diagnostics.
- Conventional radiographs of affected bones – show in the presence of rickets or osteomalacia:
- Calcified skeleton with fused bone structure (classic milk glass structure of the bones).
- Characteristic Loosersche remodeling zones (bilateral and symmetrically arranged, ligamentous, low-calcification zones; in typical localizations are lateral scapular rim (lateral scapula), proximal humerus (humerus), upper ribs, pubic bones, femoral neck, and medially on proximal femur (thigh bone)
- Possibly fish vertebrae with compaction in the top and bottom plate area of the vertebral bodies.
- Possibly pseudofractures (creeping fatigue fractures) and fissures / insufficiency fractures
- If necessary, skeletal scintigraphy – search for areas with increased bone metabolism (→ finding fracture areas (bone fractures; esp. rib fractures) in generalized bone pain).
- If necessary, magnetic resonance imaging (MRI) and computed tomography (CT) – for clarification.
- The extent of a fracture (stability?; age?).
- Of underlying metastases (daughter tumors)/tumors.
- If necessary, 18F-fluorodeoxyglucose positron emission tomography and octreotide scintigraphy – to search for tumors.
- Dual X-ray absorptiometry (DXA, DEXA; dual X-ray absorptiometry; radiographic method)/bone densitometry – to obtain baseline findings and to monitor progress.