Sarcoidosis: Or something else? Differential Diagnosis

Respiratory System (J00-J99)

  • Pulmonary fibrosisconnective tissue remodeling of the lungs leading to functional impairment.
  • Pneumoconioses – lung changes that can occur as a result of inhaling dust; e.g., asbestosis (asbestos), silicosis (quartz dust lung disease), berylliosis (beryllium).

Infectious and parasitic diseases (A00-B99).

  • HIV infection – histologic picture shows findings similar to sarcoidosis.
  • Ornithosis (parrot disease)
  • Tuberculosis (consumption) – histological picture shows granulomas, but they are caseating (caseating epitheloid cell granulomas).

Neoplasms – tumor diseases (C00-D48).

  • Malignant neoplasms such as bronchial carcinoma (lung cancer), lymphomas (malignant neoplasms originating in the lymphatic system).
  • Benign neoplasms of the lung, unspecified.

Digestive system (K00-K93)

  • Crohn’s diseasechronic inflammatory bowel disease; it usually progresses in episodes and can affect the entire digestive tract; characteristic is the segmental affection of the intestinal mucosa (intestinal mucosa), that is, several intestinal segments may be affected, which are separated by healthy sections; in approx. 0.5% of cases also bronchopulmonary diseases such as epiglottitis (inflammation of the epiglottis), laryngitis (inflammation of the larynx), tracheobronchitis (inflammation of the trachea and large bronchi), chronic bronchitis and bronchiolitis (inflammation of the small branches of the bronchial tree, called bronchioles) to necrotic nodular formations in the lung parenchyma (part of the lung where the actual breathing takes place).