Skin Aging: Or something else? Differential Diagnosis

Endocrine, nutritional, and metabolic diseases (E00-E90).

  • Chronic zinc deficiency
  • Hypothyroidism (underactive thyroid gland)

Skin and subcutaneous (L00-L99)

  • Atopic eczema (neurodermatitis)
  • Bullous pemphigoid (synonyms: parapemphigus, senile pemphigus, erythema bullosum chronicum, dermatitis herpetiformis senilis) – chronic, blistering disease with bulging, subepidermal blisters that form on reddened or normal skin; the disease occurs in the elderly and occasionally in children.
  • Eczema – dermatitis (skin inflammation), especially with pruritus (itching) and erythema (areal redness of the skin).
  • Elastosis – degeneration of the elastic fibers of the skin, which occurs with age.
  • Ichthyoses – genetic disease that leads to cornification disorders of the skin.
  • Keratosis senilis – horn and wart-like brown growths (skin patches) that occur mainly in the elderly after chronic exposure to light, with possible transition in squamous cell carcinoma.
  • Nevus cell nevi (birthmark).
  • Psoriasis vulgaris (psoriasis)
  • Pruritus senilis – itching of aging skin.
  • Purpura senilis – spontaneous skin bleeding due to vulnerable skin.
  • Seborrheic keratosis (age wart)
  • Senile angiomas – livid-reddish to glass pinhead-sized, expressible papules (circumscribed skin elevation) from benign vascular neoplasms.
  • Senile lentigines – brown sharply demarcated spots that develop with age (age spots).
  • Xeroderma (dry, brittle skin) – hypersensitivity of the skin and mucous membrane to environmental influences.

Medication