Effects
Sulfonylureas (ATC A10BB) have antidiabetic, antihyperglycemic, and insulin secretagogue properties.
Active Ingredients
1st generation:
- Tolbutamide, acetohexamide, tolazamide (all off-label).
- Chlorpropamide (Diabiformin, out of commerce).
2nd generation:
- Glibenclamide (Daonil, generic).
- Glibornuride (Glutril, off label).
- Glipizide (Glibenese, out of trade)
- Gliclazide (Diamicron /-MR, generic).
3rd generation:
- Glimepiride (Amaryl, generic).
Cf.
Diabetes mellitus type 2, glinides