Symptoms Usually beginning before the age of 20, the appearance of white patches is completely asymptomatic; the foci themselves exhibit neither itching nor scaling, are often bizarrely configured, and occasionally have darker pigmentation around the edges. A hereditary predisposition exists in one third (approx. 35%) of affected individuals. The spread is extremely variable, it can … Vitiligo (White Spot Disease)
Products Bremelanotide was approved in the United States in 2019 as an injection solution in an auto-injector pen (Vyleesi). Structure and properties Bremelanotide (C50H68N14O10, Mr = 1025.2 g/mol) is a synthetic cyclic peptide analog of α-melanocyte stimulating hormone (α-MSH) produced in the adenohypophysis. Bremelanotide consists of seven amino acids (heptapeptide) and is an active metabolite … Bremelanotide
Products Afamelanotide is administered as an implant (Scenesse, Clinuvel). It has had orphan drug status in many countries since 2008. It has not yet been registered with Swissmedic and is not approved as a drug. In the United States, the drug was approved in 2019. Structure and properties Afamelanotide is an analog of α-melanocyte-stimulating hormone … Afamelanotide
