Symptoms The possible symptoms of a transient ischemic attack (TIA) include: Visual disturbances, temporary blindness Difficulty swallowing Sensory disturbances such as numbness or formication. Speech disorders Coordination disorders, loss of balance, paralysis. Behavioral disturbances, fatigue, drowsiness, agitation, psychosis, memory impairment. The symptoms occur suddenly, are transient and last only briefly, during a maximum of one … Transient Ischemic Attack
Effects Antithrombotic Anticoagulant Fibrinolytic Active ingredients Salicylates: Acetylsalicylic acid 100 mg (Aspirin Cardio). P2Y12 antagonists: Clopidogrel (Plavix, generics). Prasugrel (Efient) Ticagrelor (Brilique) GP IIb/IIIa antagonists: Abciximab (ReoPro) Eptifibatide (Integrilin) Tirofiban (Aggrastat) PAR-1 antagonists: Vorapaxar (Zontivity) Vitamin K antagonists (coumarins): Phenprocoumon (Marcoumar). Acenocoumarol (Sintrom) Not on sale in many countries: dicoumarol, warfarin. Heparins: Heparin sodium Heparin-Calcium … Antithrombotics
Effects Fibrinolytic: dissolve fibrin Thrombolytic: dissolve thrombi Indications For the treatment of thrombosis and embolism: Myocardial infarction Ischemic stroke Deep vein thrombosis Pulmonary embolism Acute and subacute thrombosis Arterial occlusive diseases Agents Alteplase (Actilyse) Urokinase (Urokinase HS medac) Reteplase (Rapilysin, out of trade) Streptokinase (streptase, out of trade) Tenecteplase (metalysis)
Products Alteplase is commercially available as an injectable (Actilyse). The drug has been approved in many countries since 1988. Structure and properties Alteplase is a recombinant tissue plasminogen activator (rt-PA) produced by biotechnological methods. It is a serine protease composed of 527 amino acids. Effects Alteplase (ATC B01AD02) has fibrinolytic and thrombolytic properties. The enzyme … Alteplase
Products Rectogesic ointment is approved in many countries (some countries: Rectiv). Nitroglycerin ointments are also used in a higher concentration for transdermal treatment of angina (2%). This article refers to rectal administration for anal fissure. Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is nitrated glycerol. Pure nitroglycerin is explosive and … Nitroglycerin Ointment
Symptoms Possible symptoms of pulmonary embolism include: Shortness of breath (dyspnea), rapid breathing, cyanosis. Chest pain Cough with blood or sputum Rapid heartbeat Fever, sweating Loss of consciousness (syncope) Low blood pressure, shock Symptoms of deep vein thrombosis, such as a swollen, warm leg The severity varies and depends, among other things, on how large … Pulmonary Embolism Causes and Treatment
Products Tenecteplase is commercially available as an injectable (metalysis). The drug has been approved in many countries since 2000. Structure and properties Tenecteplase is a recombinant fibrin-specific plasminogen activator produced by biotechnological methods. The glycoprotein consists of 527 amino acids. The sequence is modified from native tissue-specific plasminogen activator (t-PA) at three sites. Effects Tenecteplase … Tenecteplase
