Products Tadalafil is commercially available in the form of film-coated tablets (Cialis, Adcirca, generics). It has been approved in many countries since 2004. Generics were registered in 2016 and came on the market in 2019. This article is related to erectile dysfunction treatment. Structure and properties Tadalafil (C22H19N3O4, Mr = 389.4 g/mol) exists as a … Tadalafil
Products Vardenafil is commercially available in the form of film-coated tablets and oral tablets (Levitra, co-marketing drug: Vivanza). It has been approved in many countries since 2003. Generic versions were approved in 2018. Structure and properties Vardenafil (C23H32N6O4S, Mr = 488.6 g/mol) is present in the drugs as vardenafil hydrochloride trihydrate, a piperazine derivative and … Vardenafil
Products Sildenafil is commercially available in the form of film-coated tablets and as a solution for injection (Viagra, Revatio, generics). It has been approved in many countries since 1998. Generics went on sale July 22, 2013, and the patent expired June 21. Pfizer launched auto-generic sildenafil Pfizer, identical to the original, back in May. In … Sildenafil
Products Amyl nitrite is commercially available in the form of ampoules (Amyle Nitrite Inhalant USP). The product, available in many countries, is imported from abroad and is not officially approved as a drug. Amyl nitrite is included in the Federal Office of Public Health‘s antidote list and must be stocked in hospitals for the treatment … Amyl Nitrite
Products Nitrates are commercially available in the form of chewable capsules, transdermal patches, infusion preparations, ointment, sustained-release tablets, sustained-release capsules, and sprays. As the first representative, nitroglycerin was already produced in the 19th century and used for the treatment of angina pectoris. Nitrates are thus among the oldest synthetic drugs. Structure and properties Organic nitrates … Organic Nitrates
Products Nitroglycerin is commercially available in many countries in the form of chewable capsules (Nitroglycerin Streuli). The active ingredient was produced and used medicinally as early as the 19th century. Structure and properties Nitroglycerin or glycerol trinitrate (GTN, C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an … Nitroglycerin Capsules
Products Nitroglycerin has been approved in many countries since 1981 in the form of a transdermal patch (Nitroderm, others). Structure and properties Nitroglycerin or glycerol trinitrate (C3H5N3O9, Mr = 227.1 g/mol) is an organic nitrate. It is nitrated glycerol. Nitroglycerin exists as an oily liquid and is explosive if not stabilized. Synthesis Effects Nitroglycerin (ATC … Nitroglycerin Patch
Structure and properties Potassium cyanide (KCN, Mr = 65.1 g/mol) is the potassium salt of hydrocyanic acid (HCN) and exists as a white, crystalline solid that is readily soluble in water. Potassium cyanide has a pungent taste and smells like bitter almonds. Great care should be taken when handling the substance, as poisoning can occur … Potassium Cyanide
Products Phosphodiesterase-5 inhibitors are commercially available in the form of film-coated tablets and meltable tablets. Sildenafil (Viagra) was the first active ingredient from this group to be approved in the United States, the EU, and many countries in 1998. Generics are also available today. Sildenafil was originally to be developed by Pfizer for the treatment … Phosphodiesterase-5 Inhibitors
Products Avanafil is commercially available in tablet form (Spedra, some countries: Stendra). It was approved in the US in April 2012, in the EU in 2013, and in many countries in 2016. Structure and properties Avanafil (C23H26ClN7O3, Mr = 483.95 g/mol) is a pyrimidine derivative. It exists as a white crystalline powder that is practically … Avanafil
