Apremilast is a drug used under the trade name Otezla in the treatment of plaque psoriasis and active psoriatic arthritis. It is an active substance from the group of PDE4 inhibitors. The effect of apremilast is based on inhibition of the enzyme phosphodiesterase-4. What is apremilast? Apremilast is a drug used under the trade name … Apremilast: Effects, Uses & Risks
Erythema nodosum, or nodular erythema, is an inflammatory skin condition that causes soft, nodular, and painful inflammatory reactions in the subcutaneous fatty tissue. Nodular erythema occurs on the front of the lower legs. Mainly women are affected by erythema nodosum. Nodular erythema is often, due to similar complaints and symptoms, confused by doctors with erysipelas … Erythema Nodosum (Nodular Erythema): Causes, Symptoms & Treatment
Introduction A herniated disc often results in compression of the nerve root in the spinal canal. Either the disc itself or the gelatinous content of the disc presses against the spinal cord. In this case, the nerve tissue is very sensitive and easily damaged, which can lead to pain, sensitivity disorders and possibly paralysis. Symptoms … Herniated disc with nerve damage
Determination of the degree of severity of nerve damage There are two important, common classifications for damage to peripheral nerves: the Seddon classification and the Sunderland classification. The Seddon classification of nerve injury includes three degrees of severity, while the Sunderland classification classifies nerve damage into five degrees. The severity of nerve damage depends on … Determination of the degree of severity of nerve damage | Herniated disc with nerve damage
Which ones are there? There are various cortisone preparations that are used in ophthalmology in the form of eye ointments. They contain different active ingredients, each of which can be found in different commercial preparations. The active ingredient dexamethasone, for example, is contained in Jenapharm®. Prednisolone is the active substance contained in Ultracortenol®, for example. … Eye ointment with cortisone
Side effects Possible side effects of eye ointments with cortisone can generally be allergic reactions such as skin and conjunctivitis. The eyeball may become prominent. Some people have reported stinging and burning or weeping blisters, especially if the eye ointment was used after cataract surgery. In addition, a poorer supply of the cornea and corneal … Side effects | Eye ointment with cortisone
Is the application possible during pregnancy and breastfeeding? The use of eye ointments with cortisone is possible during pregnancy and lactation, but should be avoided if possible. Since the active substance may also possibly enter the body. Particularly in the case of long-term treatment, growth disorders and damage to the unborn child may occur. If … Is the application possible during pregnancy and breastfeeding? | Eye ointment with cortisone
Metabolism Bromelain is absorbed in the human intestine and from there it enters the bloodstream. In the blood it binds to the so-called alpha2-macroglobulin. Macroglobulins are transport proteins that can bind certain substances in the blood and thus transport them to their destinations. Bromelain is rapidly metabolized by the liver and thus eliminated from the … Metabolism | Bromelain
Introduction Bromelain has anti-inflammatory and anticoagulant effects. It stands for a group of protein-degrading enzymes of certain plants. These particular enzymes are found in the pineapple plant, among others. Therefore, it is also included in the group of so-called phytotherapeutics, which are also known as herbal medicinal products. Bromelain is used by its specific effects … Bromelain
Interactions If bromelain is taken at the same time as other drugs, the uptake of the additional drug can be increased. This leads to an increase in resorption and an intensification of the effect. If an antibiotic with bromelain is taken at the same time, both the antibiotic level in the urine and the concentration … Interactions | Bromelain
Introduction The preparation Voltaren® contains the active ingredient diclofenac, which belongs to the so-called non-steroidal anti-rheumatic drugs (NSAIDs). It is used for the external treatment of pain, swelling and inflammation, and is particularly useful in rheumatic diseases or movement-related pain. Side effects As with all other drugs, side effects can occur when using Voltaren®. A … Side effects of Voltaren®
Other side effects Rarely does taking Voltaren® cause more serious gastrointestinal discomfort. These include inflammation of the stomach lining, bleeding (including bloody diarrhea or vomiting of blood) or gastrointestinal ulcers. Hypersensitivity reactions or allergic reactions are also rare, which in the worst case can even lead to a drop in blood pressure with a state … Other side effects | Side effects of Voltaren®
