Allergology is a medical specialty that deals with the development, diagnosis and treatment of allergies. Diagnosis takes place either in vitro or in vivo. In vivo testing procedures on the patient himself are sometimes associated with the risk of allergic shock for the allergy sufferer. What is allergology? Allergology is a medical specialty that deals … Allergology: Treatment, Effect & Risks
Stereognosia is the ability to recognize objects based on mere tactile experience. The postcentral region of the parietal lobe is primarily involved in this ability, in addition to the individual components of the sense of touch. Lesions in these regions can disrupt this ability and cause what is known as astereognosia (stereoagnosia). What is stereognosia? … Stereognosy: Function, Tasks, Role & Diseases
Products Erenumab (Aimovig) was the first agent from the group of CGRP inhibitors to be approved in 2018. Fremanezumab (Ajovy) and galcanezumab (Emgality) followed. Structure and properties CGRP inhibitors are humanized or human monoclonal IgG antibodies directed against calcitonin gene-related peptide (CGRP). Low-molecular-weight CGRP receptor antagonists (so-called Gepante) are in clinical development. Some agents have … CGRP Inhibitors
Emotions are one of the most important driving forces of human beings. Much more than logical thinking, emotional impulses such as hatred, contempt, anger, envy, but also pity, joy, exuberance and empathy cause us to react indirectly or directly and thus define to a considerable extent our social behavior and our social coexistence. In many … Emotions: Function, Task & Diseases
Products Pertuzumab is commercially available as a concentrate for the preparation of an infusion solution (Perjeta). It was approved in many countries in 2012. Structure and properties Pertuzumab is a recombinant humanized IgG1 monoclonal antibody. It was developed as a successor to trastuzumab (Herceptin). Effects Pertuzumab (ATC L01XC13) has cytostatic and antiproliferative properties. The effects … Pertuzumab
The motor or neuromuscular endplate, is the point of contact between a motor neuron and a muscle cell. It is also called the neuromuscular synapse and is used to transmit excitation between a motor nerve fiber and a muscle fiber. What is the motor end plate? The neuromuscular synapse is an excitatory synapse that specializes … Motor End Plate: Structure, Function & Diseases
A semen allergy is a rare allergic reaction to male semen. Like any other allergy, it results from sensitization of the immune system to certain proteins in semen. Antihistamines are an acute cure, while desensitization is a possible permanent cure for the allergy. What is a sperm allergy? Although it is very rare, allergic reactions … Sperm Allergy: Causes, Symptoms & Treatment
Products mRNA vaccines are commercially available as injectables. The first in this group to be approved in many countries was BNT162b2 from BioNTech and Pfizer on December 19, 2020. Moderna’s mRNA-1273 is also an mRNA vaccine. It was released in the EU on January 6, 2021. Both are covid-19 vaccines. Structure and properties mRNA (short … MRNA Vaccines
Products Guselkumab was approved in the United States and the EU in 2017 and in many countries in 2018 as a solution for injection for subcutaneous use (Tremfya). Structure and properties Guselkumab is an IgG1λ monoclonal antibody produced by biotechnological methods. Effects Guselkumab (ATC L04AC16) has anti-inflammatory and immunosuppressive properties. The effects are due to … Guselkumab
The elastic protein titin consists of approximately 30,000 amino acids, making it the largest known human protein. As a component of sarcomeres, the smallest contractile unit of skeletal and cardiac muscles, titin provides the elastic connection between Z-disks and myosin heads in the form of filaments. Titin filaments are passively preloaded and retract the myosin … Titin: Structure, Function & Diseases
Products Vedolizumab was approved in many countries in 2015 as a powder for a concentrate for the preparation of an infusion solution (Entyvio). In 2020, a prefilled pen and prefilled syringe were also registered. Structure and properties Vedolizumab is a humanized IgG1 monoclonal antibody with a molecular mass of 147 kDa. Effects Vedolizumab (ATC L04AA33) … Vedolizumab
Miller-Fisher syndrome is the name given to an insidious infectious disease that both disrupts movement and can also affect the speech center. The nerves as well as nerve roots are destroyed by inflammation as part of Miller-Fisher syndrome; as a result, many affected individuals are also dependent on a wheelchair. What is Miller-Fisher syndrome? The … Miller-Fisher Syndrome: Causes, Symptoms & Treatment
