Myeloblast: Structure, Function & Diseases

Myeloblasts are the most immature form of granulocytes within granulopoiesis and arise from multipotent stem cells of the bone marrow. Granulocytes are involved in the defense against infection. When there is a deficiency of granulocytes, this deficiency may result from a previous deficiency of myeloblasts and results in immunodeficiency in the sense of immune deficiency. … Myeloblast: Structure, Function & Diseases

Rice: Intolerance & Allergy

Rice is a food product derived from the rice plant. Worldwide, rice is one of the most important staple foods. Here’s what you should know about rice Rice is a food that is derived from the rice plant. Worldwide, rice is one of the most important staple foods. More than half of the world’s population … Rice: Intolerance & Allergy

Octocog Alfa

Products Octocog alfa is commercially available as an injectable. It has been approved in many countries since 2004. Structure and properties Octocog alfa is the recombinant blood clotting factor VIII produced by biotechnological methods. In the past, it was also obtained from plasma, but this posed a risk for the transmission of infectious diseases. Octocog … Octocog Alfa

Trastuzumab

Products Trastuzumab is commercially available as a lyophilizate for preparation of an infusion concentrate (Herceptin, biosimilars). It has been approved in many countries since 1999 (US: 1998, EU: 2000). In 2016, an additional solution for subcutaneous injection for breast cancer therapy was released in many countries (Herceptin subcutaneous). It was available earlier in other countries. … Trastuzumab

Elimination

Introduction Elimination is a pharmacokinetic process that describes the irreversible removal of active pharmaceutical ingredients from the body. It is composed of biotransformation (metabolism) and excretion (elimination). The most important organs for excretion are the kidney and the liver. However, drugs can also be excreted through the respiratory tract, hair, saliva, milk, tears, and sweat. … Elimination

Congenital Hypothyroidism: Causes, Symptoms & Treatment

Congenital hypothyroidism is a form of hypothyroidism. It is caused by a disorder during embryonic development. What is congenital hypothyroidism? Congenital hypothyroidism is a form of hypothyroidism. In medicine, congenital hypothyroidism also goes by the name connatal hypothyroidism or congenital hypothyroidism. It is a special form of hypothyroidism. We talk about hypothyroidism when the thyroid … Congenital Hypothyroidism: Causes, Symptoms & Treatment

B Lymphocytes: Function & Diseases

B lymphocytes (B cells) are among the white blood cells (leukocytes) and are the only cells that can also produce antibodies. If activation by foreign antigens occurs, they differentiate into memory cells or plasma cells. What are B lymphocytes? B lymphocytes are classified as part of the white blood cell group. Their most important function … B Lymphocytes: Function & Diseases

Cetuximab

Products Cetuximab is commercially available as an infusion solution (Erbitux). It has been approved in many countries since 2003. Structure and properties Cetuximab is a recombinant chimeric (human/mouse) IgG1 monoclonal antibody. It is produced by biotechnological methods. Effects Cetuximab (ATC L01XC06) has antitumor and antiangiogenic properties. It is a specific antibody against the epidermal growth … Cetuximab