Fludarabine is a cytostatic drug used for the therapy of malignant diseases. For this purpose, it is applied intravenously as an infusion. What is fludarabine? Fludarabine is a cytostatic drug used for the therapy of malignant diseases. For this purpose, it is applied intravenously as an infusion. Fludarabine, also known as fludara or fludarabine-5-dihydrogen phosphate, … Fludarabine: Effects, Uses & Risks
During erythrocyte aggregation, red blood cells cluster together and clump together. The phenomenon is physiologic to some degree, especially in the smaller capillaries. In immune complex diseases, for example, this physiologic degree is exceeded. What is erythrocyte aggregation? In erythrocyte aggregation, red blood cells cluster together and clump together. Red blood cells are also called … Erythrocyte Aggregation: Function, Role & Diseases
Products AZD1222 has been in the registration phase in the EU and many countries since the beginning of October 2020 as part of a rolling review and is not yet commercially available. The vaccine was developed at Oxford University’s Jenner Institute, spin-off Vaccitech and AstraZeneca. Efficacy and safety are being evaluated in studies involving up … AZD1222
Products Satralizumab was approved in many countries in 2020 as a solution for injection (Enspryng). Structure and properties Satralizumab is a humanized IgG2 monoclonal antibody produced by biotechnological methods. Effects Satralizumab (ATC L04AC19) has anti-inflammatory and immunosuppressive properties. The effects are due to binding to the soluble and membrane-bound human IL-6 receptor (IL-6R), preventing signal … Satralizumab
The placental barrier separates the mother’s blood circulation from that of the baby. Through this tissue filter, the two blood circulations operate independently of each other. What is the placental barrier? The placental barrier separates the mother’s bloodstream from that of the baby. Through this tissue filter, the two blood circuits operate independently of each … Placental Barrier: Function, Role & Diseases
Mineralocorticoids are hormones that belong to the corticosteroids. The hormones play an important role in regulating blood pressure and sodium/potassium balance. What are mineralocorticoids? Mineralocorticoids are steroid hormones made by the adrenal gland. Steroid hormones are steroids with hormonal effects. Steroids belong to the lipid class of substances. Lipids are molecules that have lipophilic groups … Mineralocorticoids: Function & Diseases
Procainamide is a drug belonging to the group of antiarrhythmic drugs. The substance is used primarily in the therapy of cardiac arrhythmias. What is procainamide? Procainamide is a class Ia antiarrhythmic drug. These worsen the excitability of heart cells, leading to prolongation of the action potential. As a result, the heart cells are not as … Procainamide: Effects, Uses & Risks
Products Inotuzumab ozogamicin was approved in many countries, in the EU, and in the United States in 2017 as a powder for a concentrate for the preparation of an infusion solution (Besponsa). See also under gemtuzumab ozogamicin. Structure and properties Inotuzumab ozogamicin is an antibody-drug conjugate directed against CD22. Inotuzumab is a humanized lgG4 monoclonal … Inotuzumab Ozogamicin
The descending palatine artery (descending palatal artery) is a thin extension of the maxillary artery (maxillary artery). This artery, on the other hand, opens into the external carotid artery (external carotid artery), which is directly connected to the oral cavity. The external carotid artery branches off from the common carotid artery (carotid artery) and the … Descending Palatine Artery: Structure, Function & Diseases
The ascending pharyngeal artery (ascending pharyngeal artery) is a smaller branch of the external carotid artery (carotid artery) with the latter branching off from the common carotid artery (greater carotid artery). The ascending pharyngeal artery provides blood flow to the pharynx and, with the help of a connection with the larger arteries that supply the … Ascending Pharyngeal Artery: Structure, Function & Diseases
Actin is a structural protein found in all eukaryotic cells. It participates in the assembly of the cytoskeleton and muscle. What is actin? Actin is a protein molecule with a very old developmental history. As a structural protein, it is present in the cytoplasm of every eukaryotic cell and in the sarcomere of all muscle … Actin: Function & Diseases
Products Elotuzumab was approved in the United States in 2015 and in the EU and Switzerland in 2016 as a powder for the preparation of an infusion solution (Empliciti). Structure and properties Elotuzumab is a humanized IgG1 monoclonal antibody with a molecular weight of 148.1 kDa. It is produced by biotechnological methods. Effects Elotuzumab (ATC … Elotuzumab
