Elotuzumab

Products Elotuzumab was approved in the United States in 2015 and in the EU and Switzerland in 2016 as a powder for the preparation of an infusion solution (Empliciti). Structure and properties Elotuzumab is a humanized IgG1 monoclonal antibody with a molecular weight of 148.1 kDa. It is produced by biotechnological methods. Effects Elotuzumab (ATC … Elotuzumab

Daratumumab

Products Daratumumab was approved as an infusion product in the United States in 2015 and in many countries and the EU in 2016 (Darzalex). Structure and properties Daratumumab is a humanized IgG1κ monoclonal antibody with a molecular mass of approximately 148 kDa. It is produced by biotechnological methods. Effects Daratumumab (ATC L01XC24) has antitumor and … Daratumumab

Emicizumab

Products Emicizumab was approved in the United States in 2017 and in the EU and many countries in 2018 as a subcutaneous solution for injection (Hemlibra). Structure and properties Emicizumab is a humanized and modified bispecific IgG4 monoclonal antibody that binds Factor IXa and Factor X. It is a human antibody. It has a molecular … Emicizumab

Reslizumab

Products Reslizumab was approved in the United States and EU in 2016 and in many countries in 2017 as a concentrate for the preparation of an infusion solution (Cinqaero). Structure and properties Reslizumab is a humanized IgG4/κ monoclonal antibody produced by biotechnological methods. The molecular mass is approximately 147 kDa. Effects Reslizumab (ATC R03DX08) binds … Reslizumab

Thyroid Hormones: Structure, Function & Diseases

The two thyroid hormones T3 (also triiodothyronine) and L4 (also L-thyroxine or levothyroxine) are produced in the epithelial cells of the thyroid gland. Their control is subject to the regulatory hormone TSH basal (thyroid-stimulating hormone or thyrotropin), which is produced in the pituitary gland. The classic thyroid diseases related to hormones are hyperthyroidism, hypothyroidism and … Thyroid Hormones: Structure, Function & Diseases

MERS

Symptoms Middle East respiratory syndrome (MERS) manifests as a respiratory illness with flu-like symptoms such as: Fever, chills Cough, sore throat Muscle and joint pain Shortness of breath Digestive problems such as nausea and diarrhea The disease can lead to severe pneumonia, ARDS (Acute Respiratory Distress Syndrome), septic shock, renal failure and multi-organ failure. It … MERS

Nucleic Acids

Structure and properties Nucleic acids are biomolecules found in all living things on Earth. A distinction is made between ribonucleic acid (RNA, RNA, ribonucleic acid) and deoxyribonucleic acid (DNA, DNA, deoxyribonucleic acid). Nucleic acids are polymers composed of so-called nucleotides. Each nucleotide consists of the following three units: Sugar (carbohydrate, monosaccharide, pentose): ribose in RNA, … Nucleic Acids

Alirocumab: Effects, Uses & Risks

Alirocumab is an experimental drug for hypercholesterolemia. It is one of the monoclonal antibodies. Alirocumab was introduced in May 2013 at “Pharmacon Meran” by Austrian scientist Manfred Schubert-Zsilavecz. What is alirocumab? Alirocumab is an experimental drug for hypercholesterolemia. Alirocumab functions as an inhibitor (inhibitor) of the human enzyme proprotein convertase subtilisin/kexin type 9 – PCSK9 … Alirocumab: Effects, Uses & Risks

Threonine: Function & Diseases

Threonine is an essential amino acid that can perform several functions in metabolism due to its hydroxyl group. It is a component of most proteins in the body, with a particularly high proportion present in connective tissue. Threonine occurs in four stereoisomeric forms, with only L-threonine with the (2S,3R) configuration being considered for protein construction. … Threonine: Function & Diseases

Tebipenem: Effects, Uses & Risks

Tebipenem is a medicinal agent that belongs to the group of carbapenems. Tebipenem is thus a so-called beta-lactam antibiotic, which goes back to penicillin. It is used to fight infectious diseases caused by bacteria. What is tebipenem? Tebipenem is an antibiotic that is administered to treat infectious diseases. The chemical molecular formula of the substance … Tebipenem: Effects, Uses & Risks