Tranexamic Acid

Products Tranexamic acid is commercially available in the form of film-coated tablets and effervescent tablets (Cyklokapron). It has been approved in many countries since 1968. In 2016, a solution for injection was also released. This article refers to peroral administration. Structure and properties Tranexamic acid (C8H15NO2, Mr = 157.2 g/mol) exists as a white crystalline … Tranexamic Acid

Antifibrinolytics

Definition Antifibrinolytics are drugs that inhibit the dissolution of fibrin and thus the development of bleeding. Effects Antifibrinolytic: inhibit the dissolution of fibrin and reduce blood loss due to generalized or locally increased fibrinolytic activity. Mechanism of action Antifibrinolytics are direct or indirect inhibitors of plasmin, which cleaves fibrin. Agents Amino acids: Tranexamic acid (Cyklokapron). … Antifibrinolytics

Antifibrinolytics: Effects, Uses & Risks

The term antifibrinolytics is used in pharmacology and human medicine to describe various active substances that lead to the dissolution of fibrin. Through this, antifibrinolytics prevent the development of bleeding, which is why they are also called hemorrhage or plasmin inhibitors. What are antifibrinolytics? The antifibrinolytic drug class is composed of the active ingredients tranexamic … Antifibrinolytics: Effects, Uses & Risks

Aprotinin: Effects, Uses & Risks

Aprotinin is an antifibrinolytic and as such has an inhibitory effect on the cleavage of the protein fibrin (i.e., on fibrinolysis). Because of this property, it is found in tissue adhesives. Indications include operations to create a coronary artery bypass and the very rare alpha2-antiplasmin deficiency, which is genetically determined. Because of potential risks of … Aprotinin: Effects, Uses & Risks

Tranexamic Acid: Effects, Uses & Risks

Tranexamic acid is an antifibrinolytic agent and inhibits the dissolution of blood clots. The substance is used to stop and prophylaxis bleeding caused by hyperfibrinolysis. What is tranexamic acid? The substance tranexamic acid is an antifibrinolytic agent. It inhibits the fibrinolytic system and thus ultimately inhibits clot dissolution (fibrinolysis). Tranexamic acid is produced exclusively synthetically … Tranexamic Acid: Effects, Uses & Risks