Transient Ischemic Attack

Symptoms The possible symptoms of a transient ischemic attack (TIA) include: Visual disturbances, temporary blindness Difficulty swallowing Sensory disturbances such as numbness or formication. Speech disorders Coordination disorders, loss of balance, paralysis. Behavioral disturbances, fatigue, drowsiness, agitation, psychosis, memory impairment. The symptoms occur suddenly, are transient and last only briefly, during a maximum of one … Transient Ischemic Attack

Prasugrel

Products Prasugrel is commercially available in the form of film-coated tablets (Efient). It was approved in many countries, in the EU and in the US in 2009. Generic versions were registered in 2019. Structure and properties Prasugrel (C20H20FNO3S, Mr = 373.4 g/mol) belongs to the group of thienopyridines and exists as a hydrochloride as a … Prasugrel

Clopidogrel: Drug Effects, Side Effects, Dosage and Uses

Products Clopidogrel is commercially available in tablet form (Plavix, generics). It has been approved in the United States since 1997 and in many countries and the EU since 1998. Clopidogrel is also combined with acetylsalicylic acid fixed (DuoPlavin). Structure and properties Clopidogrel (C16H16ClNO2S, Mr = 321.82 g/mol) is a thienopyridine derivative and a prodrug. It … Clopidogrel: Drug Effects, Side Effects, Dosage and Uses

Antidiabetics

Active ingredients Insulins substitute for endogenous insulin: Human insulin Insulin analogues Biguanides reduce hepatic glucose formation: Metformin (Glucophage, generic). Sulfonylureas promote insulin secretion from beta cells: Glibenclamide (Daonil, generic). Glibornuride (Glutril, off label). Gliclazide (Diamicron, generic). Glimepiride (Amaryl, generics) Glinides promote insulin secretion from beta cells: Repaglinide (NovoNorm, generic). Nateglinide (Starlix) Glitazones decrease peripheral insulin … Antidiabetics

Heart Attack Causes and Treatment

Symptoms A heart attack manifests itself in acute and severe pain and a feeling of tightness and pressure in the chest, which may also radiate to the arms, jaw or abdomen. Other symptoms include nausea, indigestion, shortness of breath, coughing, a break of sweat, pallor, fear of death, unconsciousness and dizziness. A myocardial infarction lasts … Heart Attack Causes and Treatment

Factor Xa Inhibitors

Products Direct factor Xa inhibitors are commercially available in the form of film-coated tablets and capsules. In 2008, rivaroxaban (Xarelto) was the first agent in this group to be approved in many countries and in the EU. Today, there are other drugs on the market, which are listed below. Like thrombin inhibitors, these active ingredients … Factor Xa Inhibitors

Air Travel Thrombosis

Symptoms Deep vein thrombosis develops as a result of a blood clot in the deep veins. Typical symptoms are: Painful and swollen legs and calves, edema. Redness and discoloration of the skin Locally increased temperature Often asymptomatic It poses a significant risk for the development of pulmonary embolism when part of the thrombus breaks loose … Air Travel Thrombosis

P2Y12 Antagonists

Effects P2Y12 antagonists are antiplatelet agents and prevent the formation of blood clots. The effects are due to binding to the adenosine diphosphate receptor P2Y12 on platelets. This receptor plays a central role in glycoprotein (GP)-IIb/IIa activation and platelet aggregation. The continuous binding of adenosine diphosphate (ADP) to P2Y12 is an important prerequisite for thrombus … P2Y12 Antagonists