Single administration Many medications are administered daily over a long period of time, such as agents for high blood pressure or lipid-lowering agents such as statins for disorders of lipid metabolism. However, various drugs also exist for which a single dose, i.e., a single administration, is sufficient. If necessary, it can be repeated after a … Single Dose
Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting
Products Aprepitant is commercially available in the form of capsules (Emend). It has been approved in many countries since 2003. Structure and properties Aprepitant (C23H21F7N4O3, Mr = 534.4 g/mol) is a morpholine and triazol-3-one derivative. It exists as a white crystalline powder that is practically insoluble in water. For intravenous use, the more water-soluble prodrug … Aprepitant
Symptoms Nausea is an unpleasant and painless sensation that can lead to vomiting. Vomiting is an autonomic response of the body in which the stomach contents are expelled through the mouth with contraction of the muscles. Its primary purpose is to protect the body from toxic and inedible foods and harmful substances. Nausea may be … Nausea and Vomiting
Products Fosaprepitant is commercially available as an infusion preparation (Ivemend). It has been approved in many countries since 2008. Structure and properties Fosaprepitant (C23H22F7N4O6P, Mr = 614.4 g/mol) is the prodrug of aprepitant (Emend). Unlike aprepitant, which is administered orally, fosaprepitant is administered parenterally and is more water soluble. Detailed information See under aprepitant
Products Maropitant is commercially available as a solution for injection and in tablet form as a veterinary drug (Cerenia). It has been approved in many countries since 2008. Structure and properties Maropitant (C38H50N2O9, Mr = 678.8 g/mol) Effects Maropitant (ATCvet QA04AD90) has antiemetic properties. The effects are due to inhibition of substance P binding to … Maropitant
The active ingredient aprepitant is used to prevent and suppress nausea. This can be triggered, for example, in the aftermath of surgery as well as by chemotherapy in the patient. The drug is almost invariably administered in conjunction with other remedies. What is aprepitant? The active ingredient aprepitant is used to prevent and suppress nausea. … Aprepitant: Effects, Uses & Risks
