Renander’s disease

Synonyms Bone necrosis of the sesamoid bone Introduction Renander’s disease is a disease that leads to the death (necrosis) of bone or parts of bone. Renander’s disease specifically refers to the death of the sesamoid bone of the big toe. The basis is a so-called bone infarction, which leads to a reduced supply of nutrients … Renander’s disease

Alendronic acid

Alendronic acid is a drug that is used for the treatment of osteoporosis. The drug belongs to the group of bisphosphates, which are chemical compounds containing two attached phosphate groups. However, common medicines do not contain an acid as the name “alendronic acid” suggests, but rather its salt (monosodium salt. For this reason, the name … Alendronic acid

Contraindications | Alendronic acid

Contraindications Alendronic acid must not be taken in case of any hypersensitivity and after an allergic reaction to the main active ingredient or other ingredients of the medication. In addition, patients suffering from diseases of the oesophagus (e.g. oesophagitis or reflux oesophagitis) should urgently refrain from taking this medicine, as the clinical picture could worsen. … Contraindications | Alendronic acid

Osteoclasts: Structure, Function & Diseases

Osteoclasts are giant cells responsible for bone resorption and demineralization. Their activity is regulated by various substances, such as parathyroid hormone. Too high or too low osteoclast activity shows serious effects on skeletal health. What are osteoclasts? Every seven years, humans receive an entirely new skeleton. Human bones adapt to stresses and are permanently remodeled. … Osteoclasts: Structure, Function & Diseases