Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. What is basiliximab? Basiliximab is a drug in the immunosuppressant drug class. It is used to prevent rejection after liver or kidney transplantation. Basiliximab is a drug substance that belongs to the group of chimeric … Basiliximab: Effects, Uses & Risks
Products Azathioprine is commercially available as film-coated tablets and as a lyophilizate (Imurek, generic). It has been approved in many countries since 1965. Structure and properties Azathioprine (C9H7N7O2S, Mr = 277.3 g/mol) is a nitromidazole derivative of mercaptopurine. It exists as a pale yellow powder that is practically insoluble in water. Effects Azathioprine (ATC L04AX01) … Azathioprine (Imuran)
Products Sulfasalazine is commercially available as tablets and as dragées with an enteric coating (salazopyrin, salazopyrin EN, some countries: azulfidine, azulfidine EN, or RA). It has been approved in many countries since 1950. EN stands for enteric coated and RA for Rheumatoid Arthritis. EN dragées have a coating to prevent irritation and improve gastric tolerance. … Sulfasalazine: Drug Effects, Side Effects, Dosage and Uses
Symptoms Rheumatoid arthritis is a chronic, inflammatory and systemic joint disease. It manifests as pain, symmetrically tense, achy, warm, and swollen joints, swelling, and morning stiffness that lasts for more than an hour. Initially, the hands, wrists, and feet are most affected, but later numerous other joints are also affected. Over time, deformities and rheumatoid … Rheumatoid Arthritis Causes and Treatment
Symptoms The two leading symptoms of Sjögren’s syndrome (pronounced “Schögren”) are dry mouth and dry eyes with associated symptoms such as conjunctivitis, difficulty swallowing and speaking, gingivitis, and tooth decay. The nose, throat, skin, lips and vagina are also frequently dry. In addition, many other organs may be affected less frequently and include muscle and … Sjögren’s Syndrome: Causes and Treatment
Products Febuxostat is commercially available in the form of film-coated tablets (Adenuric). It was approved in many countries in 2016. It was registered in the EU in 2008 and in the US in 2009 (US: Uloric). Structure and properties Febuxostat (C16H16N2O3S, Mr = 316.4 g/mol), unlike allopurinol, does not have a purine structure. It is … Febuxostat
Linear IgA dermatosis is an autoimmunologic disease of the skin in which the body’s immune system produces autoantibodies against adhesion proteins. The result is blistering and reddening of the skin, which in individual cases may also affect the eye. If the eyes are involved, there is a risk of blindness, which may require invasive treatment … Linear IgA Dermatosis: Causes, Symptoms & Treatment
Symptoms Irritant contact dermatitis is a common inflammatory condition of the skin. It often occurs on the hands and manifests in the following possible signs and symptoms: Redness Swellings Dry skin Scaling, often between the fingers Itching, burning, pain, tightness, tingling. Increased sensitivity, for example, to alcohol in disinfectants. Skin thickening Painful tears Crusts Erosions … Irritant Contact Dermatitis
Azathioprine is one of the immunosuppressants and has multiple uses in organ transplantation, autoimmune diseases, and certain chronic inflammatory conditions. The drug’s mode of action is mediated by inhibition of nucleic acid synthesis. Because the drug acts with delays, it is always used in combination with other immunosuppressants in organ transplantation. What is azathioprine? Azathioprine … Azathioprine: Effects, Uses & Risks
Poducts Mercaptopurine is commercially available in tablet and oral suspension form (Puri-Nethol, Xaluprine). The active ingredient has been approved in many countries since 1955. Structure and properties Mercaptopurine (C5H4N4S – H2O, Mr = 170.2 g/mol) exists as a yellow crystalline powder that is practically insoluble in water. It is an analog of the purine bases … Mercaptopurine
Products Mesalazine is commercially available as film-coated tablets, enteric-coated sustained-release tablets, granules, sustained-release granules, clysms, and suppositories (e.g., Asacol, Mezavant, Pentasa, Salofalk). It has been approved in many countries since 1984. Structure and properties Mesalazine (C7H7NO3, Mr = 153.1 g/mol) corresponds to 5-aminosalicylic acid (5-ASA). The active ingredient exists as powders or crystals that are … Mesalazine
Products Allopurinol is in the form of tablets trade (Zyloric, generic). It is approved in many countries since the year 1966. Allopurinol is also combined with the URAT1 inhibitor lesinurad. Structure and properties Allopurinol (C5H4N4O, Mr = 136.1 g/mol) exists as a white powder that is very sparingly soluble in water. It is a derivative … Allopurinol (Zyloprim)