Products Benzylpenicillin (penicillin G) is commercially available as an injectable (Penicillin Grünenthal). Structure and properties Benzylpenicillin (C16H18N2O4S, Mr = 334.4 g/mol) is present in the drug as benzylpenicillin sodium, a white crystalline powder that is very soluble in water. Other salts are also available. Benzylpenicillin is not acid stable, has low absorption, and therefore can … Benzylpenicillin
Products Rifamycin is commercially available in the form of ear drops (Otofa). It has been approved in many countries since 1988. Structure and properties Rifamycin (Rifamycin SV) is present in the drug as rifamycin sodium, a fine or slightly granular red powder that is soluble in water (C37H46NNaO12, Mr = 720 g/mol). It is obtained … Rifamycin
Products Mebucaïne f lozenges were approved in many countries in 1983 (Wander, Sandoz, Novartis, GSK). During 2018, they were replaced by Mebucaïne N lozenges with a new composition. The new drug contains the antiseptic cetylpyridinium chloride and the local anesthetic lidocaine, without the antibiotic thyrotricin. The addition of the antibiotic has been controversial for years … Mebucaine F
Products Pyrazinamide is commercially available in tablet form (Pyrazinamide Labatec, combination products). It was first used in the 1950s for the treatment of tuberculosis. Structure and properties Pyrazinamide (C5H5N3O, Mr = 123.1 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is a 1,4-pyrazine and an amide. Pyrazinamide is an … Pyrazinamide
Products Tylosin is commercially available as a solution for injection and in the form of drug premixes as a veterinary drug (Tylan). Combination preparations with chloramphenicol and sulfadimidine are also available. It has been approved in many countries since 1967 and exclusively as a veterinary drug. Structure and properties Tylosin (C46H77NO17, Mr = 916.1 g/mol) … Tylosin
Products Clindamycin is commercially available in several dosage forms. This article refers to oral administration with capsules (Dalacin C, generics). Clindamycin has been approved in many countries since 1970. Structure and properties Clindamycin (C18H33ClN2O5S, Mr = 425.0 g/mol) is a semisynthetic derivative of lincomycin obtained from (7-chloro-7-deoxy-lincomycin). In the capsules, the active ingredient is present … Clindamycin
Products The fixed combination of the lincosamide antibiotic clindamycin and the retinoid tretinoin was approved in many countries in 2014 in the form of a gel (Acnatac). In other countries, it went on sale earlier, for example in the United States, where it has been available since 2006 (Ziana). Structure and properties Clindamycin is present … Clindamycin, Tretinoin
Products Clindamycin vaginal cream has been approved in many countries since 1995 (Dalacin V). Structure and properties Clindamycin (C18H33ClN2O5S, Mr = 425.0 g/mol) is a derivative of lincomycin (7-chloro-7-deoxy-lincomycin) obtained from. It is present in vaginal cream as clindamycin phosphate, a white, slightly hygroscopic powder that is readily soluble in water. Effects Clindamycin (ATC G01AA10) … Clindamycin Vaginal Cream
Products Tetracyclines are commercially available in many countries in the form of tablets, capsules, and injection and infusion solutions, among others. This article refers primarily to peroral therapy. The first tetracycline, chlortetracycline (aureomycin, Lederle), was discovered in the 1940s during screening of soil samples under the direction of Benjamin Minge Duggar and became commercially available … Tetracycline: Drug Effects, Side Effects, Dosage and Uses
Products No drugs containing chloramphenicol for systemic use are commercially available in many countries. Structure and properties Chloramphenicol (C11H12Cl2N2O5, Mr = 323.1 g/mol) is a white to grayish white or yellowish white, fine, crystalline powder or exists as fine, acicular or elongated flat crystals. It is sparingly soluble in water. Chloramphenicol is formed during the … Chloramphenicol Effects and Side Effects
Effect Antituberculous: bacteriostatic to bactericidal (antimycobacterial). Indications Tuberculosis Active substances Antibiotics: Bedaquiline Cycloserine Delamanid Ethambutol Isoniazid Pyrazinamide Rifampicin Rifabutin Streptomycin Thioacetazone
Products Tulathromycin is commercially available as a solution for injection. It has been approved in many countries since 2005. Effects Tulathromycin (ATCvet QJ01FA94) has bacteriostatic properties. Indications For the treatment of bacterial infectious diseases in cattle and swine.
