basement membrane

Introduction Goodpasture’s syndrome, anti-glomerular basement membrane (GBM) disease/anti-GBM disease, is one of many severe but fortunately rare autoimmune diseases. In autoimmune diseases, the own body produces antibodies, i.e. actually “good defensive substances” of our body’s immune system, against the body’s own structures or cells. Normally, these antibodies are only formed after a person has come … Goodpasture syndrome

Treatment The basis of the treatment of Goodpasture’s syndrome is the administration of immunosuppressive drugs (such as cyclophosphamide) and glucocorticoids (i.e. cortisone) and a plasma exchange (“plasmapheresis”) to remove the circulating antibodies.The survival after 1 year in a British retrospective is 100% and the survival of the kidneys is 95%. According to recent findings, an … Treatment | Goodpasture syndrome