Gamma Hydroxybutyrate (GHB)

Products Gammahydroxybutyrate is commercially available as an oral solution (Xyrem). It has been approved in many countries since 2006. The drug belongs to narcotics and requires an aggravated prescription. GHB is also known to be manufactured and trafficked illegally. Structure and properties The free γ-hydroxybutyric acid (C4H8O3, Mr = 104.1 g/mol) is a colorless and … Gamma Hydroxybutyrate (GHB)

Neuraminidase Inhibitor

Products Neuraminidase inhibitors are commercially available in the form of capsules, powder for oral suspension, powder inhalers, and injectables. The first agents to be approved were zanamivir (Relenza) in 1999, followed by oseltamivir (Tamiflu). Laninamivir (Inavir) was released in Japan in 2010 and Peramivir (Rapivab) in the USA in 2014. The public is most familiar … Neuraminidase Inhibitor

Lidocaine: Effects, Uses & Risks

Lidocaine is a drug in the local anesthetic class that also acts as an antiarrhythmic agent. It belongs to the sodium channel blocker group. What is lidocaine? Lidocaine is a drug in the local anesthetic class that also acts as an antiarrhythmic agent. The drug lidocaine was the first amino-amide local anesthetic. It was synthesized … Lidocaine: Effects, Uses & Risks

ADME

Pharmacodynamics and pharmacokinetics. When we take a tablet, we are usually interested in its immediate effects. The drug is supposed to relieve a headache or reduce symptoms of a cold. At the same time, we may think about the possible side effects it may trigger. The desired and undesired effects that a drug exerts on … ADME

Valaciclovir: Effects, Uses & Risks

Valaciclovir is one of the most commonly used agents to combat herpes simplex virus infection and shingles. The drug is incorporated into numerous preparations, is a prodrug, and is considered a virostatic agent. What is valaciclovir? Valaciclovir is a prodrug of aciclovir used in the therapy of herpes infections and shingles. The term prodrug is … Valaciclovir: Effects, Uses & Risks

Antacids to Neutralise Stomach Acid

Products Antacids are commercially available in the form of lozenges, chewable tablets, as a powder, and as a gel (suspension) for oral use, among others. Well-known brands in many countries include Rennie, Alucol, and Riopan. The first medicines were developed as early as the 19th century. Structure and properties The drugs contain active ingredients that … Antacids to Neutralise Stomach Acid

Valganciclovir: Effects, Uses & Risks

Valganciclovir is a virostatic agent used to treat cytomegalovirus retinitis (inclusion body disease) occurring in AIDS patients. The drug belongs to the group of nucleoside analogues and is widely used. As a prodrug of the substance ganciclovir, it has essentially the same effects and side effects as the latter. What is valganciclovir? Valganciclovir is a … Valganciclovir: Effects, Uses & Risks

Cromoglicic Acid in Asthma

Products Cromoglicic acid had been approved for asthma therapy in many countries since 1969. After the original Lomudal, the generic Cromosol UD also went off the market in 2016. Medicines for inhalation are still available in Germany. Structure and properties The drugs contain sodium cromoglicate (C23H14Na2O11, Mr = 512.3 g/mol), a white, crystalline, hygroscopic powder … Cromoglicic Acid in Asthma

Multivitamin Supplements

Products Multivitamin preparations are commercially available in the form of tablets, effervescent tablets, chewable tablets and juice, among others. Among the best-known brands in many countries are, for example, Burgerstein CELA, Centrum and Supradyn. Some products are approved as medicines and others as dietary supplements. Supradyn (Bayer) was originally manufactured by Roche and has been … Multivitamin Supplements

Alumina

Products Hydrous alumina is commercially available in combination with magnesium hydroxide as a suspension and in the form of chewable tablets (Alucol). It has been approved in many countries since 1957. Structure and properties Alumina (Al2O3, Mr = 102.0 g/mol) is the oxide of aluminum. Hydrous alumina, as defined by the pharmacopoeia, contains 47 to … Alumina

Iron Maltol

Products Ferric maltol is commercially available in the form of hard capsules (Feraccru, some countries: Accrufer). It was approved in the EU in 2016 and in many countries in 2017. Structure and properties Ferric maltol contains ferric ions in a complex with three molecules of maltol (ferric trimaltol). Due to the complexation, iron is better … Iron Maltol

Procainamide: Effects, Uses & Risks

Procainamide is a drug belonging to the group of antiarrhythmic drugs. The substance is used primarily in the therapy of cardiac arrhythmias. What is procainamide? Procainamide is a class Ia antiarrhythmic drug. These worsen the excitability of heart cells, leading to prolongation of the action potential. As a result, the heart cells are not as … Procainamide: Effects, Uses & Risks