TNM classification of gallbladder carcinoma.
| T | N | M | |
| X | Primary tumor not assessable | Lymph nodes not assessable | Distant metastases not assessable |
| 0 | No evidence of tumor | Lymph nodes not affected | No distant metastases |
| Tis | Tumor in situ (carcinoma in situ) | ||
| 1 | Infiltration (penetration) of lamina propria/thin layer of connective tissue located just below an epithelium (T1a) Infiltration of muscle (T1b) | Regional lymph nodes affected | Distant metastases present |
| 2 | Infiltration of perimuscular connective tissue | ||
| 3 | Perforation (breakthrough) of serosa and/or a neighboring organ | ||
| 4 | Infiltration of portal vein, hepatic artery, and/or two or more adjacent organs |
UICC stage (“Union internationale contre le cancer“, UICC).
| Stage | T | N | M |
| 0 | Tis | 0 | 0 |
| I | 1 | 0 | 0 |
| II | 2 | 0 | 0 |
| III | 3 1-3 | 0 1 | 0 0 |
| IV | 4 each | each each | 0 1 |
The following histological forms of gallbladder carcinoma can be distinguished:
- Adenomatous (glandular epithelium-like) carcinoma.
- Anaplastic (dedifferentiated) carcinoma
- Squamous cell carcinoma
- Cirrhotic (connective tissue hardened) carcinoma.
