Sotalol is a pharmacological agent that belongs to the beta-blocker category. The drug is primarily used for the treatment of cardiac arrhythmias. Sotalol is a special beta-blocker that does not have a phenol ether structure. In its structure, the substance also resembles beta-isoprenaline. What is sotalol? The drug sotalol is among those beta-blockers that are … Sotalol: Effects, Uses & Risks
Hydrochlorothiazide is a diuretic drug and is considered the prototype of thiazide diuretics. The active ingredient is used, among other things, to treat edema. What is hydrochlorothiazide? Hydrochlorothiazide acts on the distal tubules of the nephron. The nephron is the smallest functional unit of the kidney. Hydrochlorothiazide is a diuretic. Diuretics are drugs with a … Hydrochlorothiazide: Effects, Uses & Risks
Products Zinc is found in numerous pharmaceutical products. This article refers to peroral administration, for example, in the form of tablets, chewable tablets, lozenges, and effervescent tablets. Zinc should not be confused with tin. Structure and properties Zinc (Zn) is a chemical element with an atomic number of 20 that exists as a brittle, blue-silver … Zinc
Products Zanamivir is commercially available as a dischaler for powder inhalation (Relenza). It has been approved in many countries since 1999. Zanamivir is far less well known than oseltamivir (Tamiflu), probably mainly because of its more complicated administration. Structure and properties Zanamivir (C12H20N4O7, Mr = 332.3 g/mol) exists as a white powder. It has a … Zanamivir
Products Rivaroxaban is commercially available in the form of film-coated tablets (Xarelto, Xarelto vascular). It was approved in 2008 as the first agent in the direct factor Xa inhibitor group. Low-dose Xarelto vascular, 2.5 mg, was registered in many countries in 2019. Structure and properties Rivaroxaban (C19H18ClN3O5S, Mr = 435.9 g/mol) is a pure -enantiomer … Rivaroxaban
Products Diltiazem is commercially available in tablet and capsule form (Dilzem, generic). It has been approved in many countries since 1982. Structure and properties Diltiazem (C22H26N2O4S, Mr = 414.52 g/mol) is a benzothiazepine derivative. It is present in drugs as diltiazem hydrochloride, a white crystalline powder with a bitter taste that is readily soluble in … Diltiazem
Products Misoprostol tablets for medication abortion were approved in many countries in 2015 (MisoOne). This article refers to abortion. In addition, other drugs exist with other indications (gastric protection, induction of labor). Structure and properties Misoprostol (C22H38O5, Mr = 382.5 g/mol) is a synthetic derivative of prostaglandin E1 and exists as a mixture of two … Misoprostol
Intestinal absorption After ingestion of a drug, the active ingredient must first be released. This process is called release (liberation), and it is a prerequisite for subsequent absorption. Absorption (formerly: resorption) is the passage of an active pharmaceutical ingredient from the digestive pulp into the bloodstream in the stomach and intestines. Absorption occurs primarily in … Absorption
Products Bisphosphonates are commercially available in the form of film-coated tablets and as injection and infusion preparations. They are also combined fixed with vitamin D3. Their effects on bone were described in the 1960s. Etidronate was the first active ingredient to be approved (out of trade). Structure and properties Bisphosphonates contain a central carbon atom … Bisphosphonates Effects and Side Effects
Products Most ACE inhibitors are commercially available in the form of tablets and film-coated tablets. The first agent from this group to be approved was captopril, in many countries in 1980. ACE inhibitors are often combined with the thiazide diuretic hydrochlorothiazide (HCT) fix. Structure and properties ACE inhibitors are peptidomimetics derived from peptides found in … ACE Inhibitors List, Effects, Side Effects
Products Caspofungin must be administered as an infusion solution because of its low oral bioavailability (Cancidas, generics). It has been approved in many countries since 2002 and was the first member of the echinocandins. Structure and properties Caspofungin is present in drugs as caspofungin diacetate (C52H88N10O15 – 2C2H4O2, Mr = 1213.42 g/mol), a hygroscopic white … Caspofungin
Products Many drugs are available in the form of suppositories. The most commonly administered in the office are acetaminophen suppositories for the treatment of fever and pain in infants and children (photo, click to enlarge). Definition Suppositories are single-dose medicinal preparations with a solid consistency. They usually have an elongated, torpedo-like shape and a smooth … Suppositories (Suppositories)
