Products Azaperone is commercially available as a solution for injection (Stresnil). It has been approved in many countries since 1970. Structure and properties Azaperone (C19H22FN3O, Mr = 327.4 g/mol), like haloperidol (haldol), belongs to the butyrphenones. It is a white powder that is practically insoluble in water. Effects Azaperone (ATCvet QN05AD90) is depressant and effective … Azaperone
Products Antiemetics are commercially available in the form of tablets, as melting tablets, as solutions (drops), and injectables, among others. They are also administered as suppositories because peroral administration is not possible. In many countries, the best-known antiemetics include domperidone (Motilium, generic) and meclozine, which, along with caffeine and pyridoxine, is contained in Itinerol B6. … Antiemetics: Drugs against Nausea or Vomiting
Products Droperidol is commercially available as a solution for injection (Droperidol Sintetica). It has been approved in many countries since 2006. Structure and properties Droperidol (C22H22FN3O2, Mr = 379.4 g/mol) structurally belongs to the butyrphenones and exists as a white powder that is practically insoluble in water. It is a benzimidazolinone derivative. Effects Droperidol (ATC … Droperidol
Products Haloperidol is commercially available as tablets, drops (Haldol), and as a solution for injection (Haldol, Haldol decanoas). It has been approved in many countries since 1960. Structure and properties Haloperidol (C21H23ClFNO2, Mr = 375.9 g/mol) is a derivative of pethidine, which is itself derived from atropine. It has structural similarity to loperamide. Haloperidol exists … Haloperidol
Products There are no drugs containing bromperidol on the market in many countries. Structure and properties Bromperidol (C21H23BrFNO2, Mr = 420.3 g/mol) exists as a white powder that is practically insoluble in water. It is identical to haloperidol but is brominated instead of chlorinated. Bromperidol is a butyrphenone derivative. Bromperidol decanoate (depot injection) is also … Bromperidol
Products Domperidone is commercially available as film-coated tablets, lingual tablets, and as a suspension (Motilium, generics). It was synthesized in 1974 and has been approved in many countries since 1979. Structure and properties Domperidone (C22H24ClN5O2, Mr = 425.9 g/mol) exists as a white powder that is practically insoluble in water. It is a benzimidazole derivative … Domperidone
Effects Dopamine antagonists are antidopaminergic, antipsychotic, antiemetic, and prokinetic. They are antagonists at dopamine receptors, eg, dopamine (D2)-receptors, thus abolishing the effects of the neurotransmitter dopamine. Indications Psychotic disorders Nausea and vomiting, to promote gastric emptying and motility in the gastrointestinal tract. Some dopamine antagonists are also used to treat movement disorders (dyskinesias, including neuroleptic-induced), … Dopamine Antagonists
Products Pipamperone is commercially available in tablet form (dipiperone). It has been approved in many countries since 1964. Structure and properties Pipamperone (C21H30FN3O2, Mr = 375.5 g/mol) is present in drugs as pipamperondihydrochloride. It is structurally closely related to haloperidol, which also belongs to the butyrphenones. Butyrphenones, like numerous other active ingredients, originated in the … Pipamperon
