Phosphates play a crucial role in the organism for the maintenance of many life processes. Phosphate metabolism and calcium metabolism are closely related. Both a phosphate deficiency and a phosphate excess cause severe health complaints, which can also lead to death. What is phosphate metabolism? Phosphates, as anions of phosphoric acid, are involved in all … Phosphate Metabolism: Function, Tasks, Role & Diseases
Introduction Hormonal drugs are various drugs that contain hormones. Hormones are endogenous substances that are not absorbed through food. For example, there are sex hormones, thyroid hormones, pituitary hormones, pancreatic hormones such as insulin or glucagon, and adrenal hormones such as aldosterone. The most commonly used hormonal drugs contain sex hormones, either female sex hormones, … Hormonal drugs
Hormonal drugs for men Only rarely does a man have to take hormonal medication containing sex hormones. However, it is possible that a patient may produce too few male sex hormones (testosterone), for example due to castration. In this case a patient may be given hormonal medication containing the hormone testosterone. Among other things, this … Hormonal drugs for men | Hormonal drugs
Hormonal drugs in acute situations During an acute situation, such as an operation or even in the event of circulatory arrest, shock or cardiac arrest, a doctor may administer certain hormonal drugs to a patient. These are usually given (applied) via the vein, a blood vessel that usually transports blood that is low in oxygen. … Hormonal drugs in acute situations | Hormonal drugs
Idiopathic juvenile osteoporosis is the occurrence of bone loss in children and adolescents. The cause of the condition is unknown. What is idiopathic juvenile osteoporosis? Idiopathic juvenile osteoporosis (IJO) is a form of bone loss that presents in childhood and adolescence. It is also called Dent-Friedman syndrome because it was named after the medical doctors … Idiopathic Juvenile Osteoporosis: Causes, Symptoms & Treatment
Products Salmcalcitonin is commercially available as a nasal spray and solution for injection (Miacalcic). It has been approved in many countries since 1976. Structure and properties The drug does not contain the human thyroid hormone calcitonin, but salmon calcitonin, also known as salmcalcitonin. It is a synthetic polypeptide consisting of 32 amino acids (C145H240N44O48S2, Mr … Salmcalcitonin
Parathyroid hormone or parathyrin is produced in the parathyroid glands. The hormone plays a significant role in the regulation of calcium and phosphate balance. What is parathyroid hormone? Parathyroid hormone (parathyrin, PTH) is a linear polypeptide hormone produced by the parathyroid glands (glandulae parathyreoideae, epithelial corpuscles) and consists of a total of 84 amino acids. … Parathyroid Hormone (Parathyrin): Function & Diseases
Proteohormones represent the largest group of hormones with various functions in the organism. They are composed of chains of amino acids linked by peptide bonds and are all water-soluble. What are proteohormones? Proteohormones are composed of peptide chains of amino acids. Among them are long-chain proteins with a chain length of more than 100 amino … Proteohormones: Function & Diseases
The term giant cells comes from histology or pathology. Giant cells are cells that are greatly enlarged and have multiple nuclei. What are giant cells? In histology and pathology, the term giant cell refers to a cell that is very large compared to other cells. Giant cells usually have multiple nuclei. These may be misshapen … Giant Cells: Structure, Function & Diseases
If Paget’s disease is suspected, an X-ray examination will usually confirm the diagnosis: The rapid, “sloppy” bone formation, structural changes, thickening and deformation of the bone tissue can be easily seen. A bone scintigraphy may be taken to show the increased metabolic activity in the bone. Supportive blood or urine tests are performed, which show … Paget’s Disease: Therapy and Diagnosis
In healthy bone, formation and degradation are in balance. This is disturbed in Paget’s disease. Many patients are symptom-free, while others experience various symptoms. Paget’s disease is named after its first describer, the British physician Sir James Paget. It is also called “Paget’s disease of the bone” (to distinguish it from Paget’s carcinoma, “Paget’s disease … Paget’s Disease: Symptoms, Diagnosis, Therapy
Craniodiaphyseal dysplasia is a congenital skeletal disorder associated with hyperostosis and sclerosis in the facial skull. The cause is a genetic mutation of bone-building inhibitory genes. Therapy is symptomatic and focuses on halting disease progression. What is craniodiaphyseal dysplasia? In hyperostosis, bone substance multiplies in an abnormal way. Hyperostosis of the skull is a group … Craniodiaphyseal Dysplasia: Causes, Symptoms & Treatment
