carfilzomib

Carfilzomib

Products Carfilzomib was approved in many countries in 2015 as a powder for the preparation of an infusion solution (Kyprolis). Structure and properties Carfilzomib (C40H57N5O7, Mr = 719.9 g/mol) exists as a crystalline substance that is practically insoluble in water. It is a peptide derivative, a tetrapeptide epoxyketone. Epoxyketones are derivatives of epoxomicin, a natural … Carfilzomib

Bortezomib

Products Bortezomib is commercially available as a lyophilizate for the preparation of a solution for injection (Velcade). It has been approved in many countries since 2005. Generic versions were registered in 2018. Structure and properties Bortezomib (C19H25BN4O4, Mr = 384.2 g/mol) is a dipeptidyl derivative of boric acid. Effects Bortezomib (ATC L01XX32) has cytotoxic and … Bortezomib