cholestasis

Flucloxacillin: Effects, Uses & Risks

Flucloxacillin is a so-called narrow-spectrum antibiotic. Unlike broad-spectrum antibiotics, it is only effective against a small number of pathogens. Flucloxacillin belongs to the pharmacological group of penicillins and more precisely to the isoxazolylpenicillins. Primarily, the drug is used for the therapy of infectious diseases caused by Staphylococcus aureus. What is flucloxacillin? Flucloxacillin is a so-called … Flucloxacillin: Effects, Uses & Risks

Simvastatin: Effects, Uses & Risks

Simvastatin is a classic statin and is used as a cholesterol-lowering agent. It was approved in 1990 and is used relatively frequently. What is simvastatin? Simvastatin, chemically (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl-2,2-dimethylbutanoate, is a drug used primarily as a cholesterol-lowering agent. Simvastatin is structurally derived from the naturally occurring monacolin K, also known as lovastatin. Simvastatin is partially synthetically … Simvastatin: Effects, Uses & Risks

Phenylbutazone: Effects, Uses & Risks

Phenylbutazone belongs to the non-steroidal anti-inflammatory drug group. It is used to treat inflammation, pain, and fever. What is phenylbutazone? Phenylbutazone belongs to the non-steroidal anti-inflammatory drug group. It is used to treat inflammation, pain, and fever. The drug phenylbutazone is used both in human medicine and in veterinary medicine. There, based on pyrazolone, an … Phenylbutazone: Effects, Uses & Risks

Clarithromycin: Effects, Uses & Risks

The active medical ingredient clarithromycin is a macrolide antibiotic. The drug is primarily used for the treatment of bacterial respiratory tract infections. What is clarithromycin? The active medical ingredient clarithromycin is a macrolide antibiotic. The drug is primarily used for the treatment of bacterial respiratory tract infections. Clarithromycin belongs to the group of macrolide antibiotics. … Clarithromycin: Effects, Uses & Risks

Progressive Familial Intrahepatic Cholestasis: Causes, Symptoms & Treatment

The term progressive familial intrahepatic cholestasis is used to describe three cholestases that are very similar in appearance and can be distinguished from each other by different genetic defects. The diseases are inherited in an autosomal recessive manner and lead to a stasis of bile fluids in the body due to defectively encoded membrane transport … Progressive Familial Intrahepatic Cholestasis: Causes, Symptoms & Treatment

Proopiomelanocortin: Function & Diseases

Proopiomelanocortin (POMC) is a so-called prohormone from which over ten different active hormones can be formed. The prohormone is synthesized in the adenohypophysis, hypothalamus, and placenta and epithelia to express the corresponding hormones. Deficiency of POMC leads to severe hormonal imbalances in the organism. What is proopiomelanocortin? Proopiomelanocortin is a protein composed of 241 different … Proopiomelanocortin: Function & Diseases

Hepatology: Treatment, Effects & Risks

The medical specialty of hepatology deals with the dysfunctions and diseases of the liver. The term hepar is the Greek name for the organ that performs numerous important tasks in metabolism, blood formation and detoxification of the organism. What is hepatology? The medical specialty of hepatology deals with the functional disorders and diseases of the … Hepatology: Treatment, Effects & Risks

Peptidase: Function & Diseases

Peptidases are enzymes that can cleave peptide bonds of peptides and proteins catalytically by hydrolization, i.e., via the addition of an H2O molecule. Peptidases are active extracellularly and intracellularly. They are involved not only in the degradation of proteins and peptides for energy production and to obtain fragments for the construction of new proteins, but … Peptidase: Function & Diseases

Bile duct

Synonyms Bile ductThe bile duct belongs to a duct system between the liver, pancreas and intestine. In this system, bile flows from the liver to the duodenum. In the broadest sense, the gallbladder can also be counted among the bile duct system. Anatomy Bile is formed in the liver. In addition to water, this bile … Bile duct