Antiasthmatics

1. symptom treatment Beta2-sympathomimetics are derived from epinephrine. They selectively stimulate the adrenergic β2-receptors of bronchial muscles and thus have a bronchospasmolytic effect. For rapid symptom relief, fast-acting agents are usually administered by inhalation, for example, with a metered-dose inhaler or a powder inhaler. They should be used only when needed. An increase in administration … Antiasthmatics

Inhaled Glucocorticoids

Effects Glucocorticoids (ATC R03BA02) have anti-inflammatory, antiallergic, and immunosuppressive properties. The effects are based on binding to intracellular receptors, resulting in an influence on protein expression. In addition, glucocorticoids also exert extragenomic effects. All agents are lipophilic (virtually insoluble in water) and thus enter cells well across the cell membrane. Indications For the treatment of … Inhaled Glucocorticoids

Ciclesonide

Products Ciclesonide is administered with a metered-dose inhaler (Alvesco). It has been approved in many countries since 2006. In the United States, it has also been commercially available as a nasal spray for the treatment of allergic rhinitis since 2012 (Zetonna). Structure and properties Ciclesonide (C32H44O7, Mr = 540.7 g/mol) is a prodrug and is … Ciclesonide

Cortisone therapy for asthma

Introduction Glucocorticoids (cortisone) are, along with beta-2 sympathomimetics, the most important group of drugs in the treatment of chronic inflammatory lung diseases such as bronchial asthma or COPD (chronic obstructive pulmonary disease). Used as a respiratory spray or powder, they enter the lungs and bronchi directly. There, glucocorticoids control the development of inflammation of the … Cortisone therapy for asthma

Cortisone shock therapy | Cortisone therapy for asthma

Cortisone shock therapy In cortisone shock therapy, very high doses of cortisone are applied for a short period of time in the acute phase of a disease in order to achieve rapid relief of symptoms. The cortisone dose is then reduced relatively quickly to a dose that corresponds approximately to the Cushing’s threshold. Such a … Cortisone shock therapy | Cortisone therapy for asthma

What’s the Cushing’s threshold? | Cortisone therapy for asthma

What’s the Cushing’s threshold? The Cushing’s threshold is understood to be the maximum dose of cortisone preparations that can still be taken daily without the risk of developing a so-called Cushing’s syndrome. If high-dose therapy with cortisone preparations is continued over a longer period of time, there is a risk that the oversupply of cortisol … What’s the Cushing’s threshold? | Cortisone therapy for asthma

What are the alternatives to cortisone? | Cortisone therapy for asthma

What are the alternatives to cortisone? The cortisone preparations most frequently used in asthma therapy are budesenoside and beclomethasone. In addition to these cortisone preparations, beta-2 sympathomimetics play a particularly important role in asthma therapy. However, they differ significantly in their effect from the cortisone preparations mentioned. While the inhaled cortisosteroids have a long-term anti-inflammatory … What are the alternatives to cortisone? | Cortisone therapy for asthma

Which asthma medicines contain cortisone? | Medicines for bronchial asthma

Which asthma medicines contain cortisone? Many medications used to treat asthma contain cortisone. The standard preparation for long-term asthma control is glucocorticoids, which usually contain cortisone or agents similar to cortisone. Glucocorticoids used in asthma are beclometasone, budesonide and fluticasone. However, these are usually very effective. Alternatively, leukotriene receptor antagonists (LTRA) can be used for … Which asthma medicines contain cortisone? | Medicines for bronchial asthma