cotrimoxazole

Cotrimoxazole: Effects, Applications, Side Effects

How cotrimoxazole works Cotrimoxazole is a combination preparation of the antibiotics sulfamethoxazole and trimethoprim. Both substances inhibit the formation of folic acid in certain bacteria and fungi. This is needed for the synthesis of some building blocks of genetic material (thymidine and purines). Cotrimoxazole interrupts folic acid synthesis in two different ways: Trimethoprim inhibits the … Cotrimoxazole: Effects, Applications, Side Effects

Cat Scratch Disease

Symptoms Classic cat scratch disease first manifests as a red papule or pustule at the site where the cat scratched or bit. Soon, local lymphadenitis (inflammation and swelling of the lymph nodes) occurs on the side of the body with the injury, often on the armpit or neck. Children and adolescents are particularly affected. Other … Cat Scratch Disease

Klebsiella Granulomatis: Infection, Transmission & Diseases

Klebsiella granulomatis is an unflagellated, Gram-negative, rod-shaped bacterium of the Enterobacteriaceae family. It lives facultatively anaerobically in the cytoplasm of large, mononuclear cells and is the causative agent of the venereal disease donovanosis. The bacterium does not form spores and therefore depends on direct human-to-human transmission, usually through sexual intercourse, for longer-term survival. What is … Klebsiella Granulomatis: Infection, Transmission & Diseases

Prolongation of the QT Interval

Symptoms Drug-induced prolongation of the QT interval can rarely lead to severe arrhythmias. This is polymorphic ventricular tachycardia, known as torsade de pointes arrhythmia. It can be seen on the ECG as a wave-like structure. Due to the dysfunction, the heart cannot maintain blood pressure and can only pump insufficient blood and oxygen to the … Prolongation of the QT Interval

Pubic Lice (Crabs): Causes and Treatment

Symptoms Itching Lice and nits in the pubic hair Gray to blue skin patches (maculae ceruleae, “taches bleues”) at the injection sites Reddish brown spots on the underwear Causes The blood-sucking crab louse is a wingless insect about 1 to 2 mm long with 6 legs and large foot claws on the 2nd and 3rd … Pubic Lice (Crabs): Causes and Treatment

Listeriosis: Causes, Symptoms & Treatment

Listeriosis is an infectious disease caused mainly by contaminated food. For healthy people, listeriosis is rather harmless, but for pregnant women, weakened or elderly people, the infection can be dangerous. What is listeriosis? Listeriosis is transmitted by so-called listeria. These are bacteria of the genus Listeria, which are very undemanding and therefore widespread. They occur … Listeriosis: Causes, Symptoms & Treatment

Listeria Monocytogenes: Infection, Transmission & Diseases

Listeria monocytogenes is a species of bacteria belonging to the Firmicutes division. The germ belongs to the genus Listeria. The genus name Listeria was named after the English surgeon Joseph Lister. The species name Monocytogenes was chosen because of monocytosis, which is often caused by Listeria monocytogenes. What is Listeria monocytogenes? The bacterium has a … Listeria Monocytogenes: Infection, Transmission & Diseases

Listeria: Infection, Transmission & Diseases

Listeria is commonly found in raw foods such as ground meat, raw milk, fish, and salads. They are extremely adaptable bacteria that can be found all over the world and require few nutrients to survive. The resilience of these bacteria is demonstrated by the fact that they can survive even in the absence of air … Listeria: Infection, Transmission & Diseases

Cystitis: Inflammation of the Bladder

Symptoms Acute, uncomplicated bladder infections are among the most common infectious diseases in women. A bladder infection is considered uncomplicated or simple when the urinary tract is functionally and structurally normal and there are no diseases that promote infection, for example, diabetes mellitus or immunosuppression. Symptoms include: Painful, frequent and difficult urination. Strong urge to … Cystitis: Inflammation of the Bladder

Trimethoprim and Sulfamethoxazole

Products Trimethoprim and sulfamethoxazole are commercially available in tablet and syrup form (Bactrim, generics). The drug has been approved in many countries since 1969. The Bactrim syrup is no longer available, but a generic is available (Nopil syrup). The fixed combination of the two active ingredients is also called cotrimoxazole. Structure and properties Trimethoprim (C14H18N4O3, … Trimethoprim and Sulfamethoxazole

Trimethoprim: Effects, Uses & Risks

The active substance trimethoprim is an antibiotic that belongs to the category of diaminopyrimidines. The drug is used in the treatment of infections caused by bacteria. The drug trimethoprim is especially frequently used for the treatment of cystitis in female patients. As a rule, the drug is taken in the morning and evening after meals. … Trimethoprim: Effects, Uses & Risks

Pneumocystis Pneumonia: Causes, Symptoms & Treatment

Every year, more than 600,000 people in Germany alone contract pneumonia, technically known as pneumonia. This inflammation of the lung tissue can have different causes and is divided into several subcategories. A particularly dangerous form of pneumonia is Pneumocystis pneumonia (PCP). What is pneumocystis pneumonia? Pneumocystis pneumonia is an interstitial type of pneumonia. In other … Pneumocystis Pneumonia: Causes, Symptoms & Treatment