Products Zolmitriptan is commercially available as film-coated tablets, meltable tablets, and as a nasal spray (Zomig, generics). It has been approved in many countries since 1997. Generic versions entered the market in 2012. Structure and properties Zolmitriptan (C16H21N3O2, Mr = 287.4 g/mol) is an indole and oxazolidinone derivative structurally related to serotonin. It exists as … Zolmitriptan
Products Duloxetine is commercially available in the form of capsules (Cymbalta, generic). It has been approved in many countries since 2005. Structure and properties Duloxetine (C18H19NOS, Mr = 297.4 g/mol) is present in drugs as pure -duloxetine hydrochloride, a white to light brown powder that is sparingly soluble in water. Effects Duloxetine (ATC N06AX21) has … Duloxetine
Products Agomelatine is commercially available in the form of film-coated tablets (Valdoxan, generic). It was approved in the EU in 2009 and in many countries in 2010. Structure and properties Agomelatine (C15H17NO2, Mr = 243.30 g/mol) exists as a white powder that is practically insoluble in water. It is a naphthalene analog of the epiphyseal … Agomelatine
Products Tizanidine is commercially available in tablet and sustained-release capsule form (Sirdalud, Sirdalud MR, generics). It has been approved in many countries since 1983. Structure and properties Tizanidine (C9H8ClN5S, Mr = 253.7 g/mol) is present in drugs as tizanidine hydrochloride, a white crystalline powder that is somewhat soluble in water. It is an imidazoline and … Tizanidin
Products Vemurafenib was approved in 2011 in film-coated tablet form (Zelboraf). Structure and properties Vemurafenib (C23H18ClF2N3O3S, Mr = 489.9 g/mol) is a white, crystalline substance that is practically insoluble in water. Effects Vemurafenib (ATC L01XE15) has antitumor and antiproliferative properties. It reduces mortality and increases survival. The properties are based on inhibition of the mutant … Vemurafenib
Products Tasimelteon was approved in the United States in 2014 and in the EU in 2015 in capsule form (Hetlioz). The drug is not currently registered in many countries. Structure and properties Tasimelteon (C15H19NO2, Mr = 245.3 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is structurally related to … Tasimelteon
Products Ropivacaine is commercially available as a solution for injection (Naropin, generic). It has been approved in many countries since 1997. Structure and properties Ropivacaine (C17H26N2O, Mr = 274.4 g/mol) is present in drugs as ropivacaine hydrochloride monohydrate. It was developed as a pure -enantiomer and belongs to the lipophilic amide-type local anesthetics. Ropivacaine is … Ropivacaine
