Products Zolpidem is commercially available as film-coated tablets, sustained-release tablets, and effervescent tablets (Stilnox, Stilnox CR, generics, USA: Ambien). It has been approved in many countries since 1990. Structure and properties Zolpidem (C19H21N3O, Mr = 307.39 g/mol) is an imidazopyridine that is structurally distinct from the benzodiazepines. It is present in drugs as zolpidem tartrate, … Zolpidem
Products Cariprazine was approved in the United States in 2015 and in many countries and the EU in 2018 in capsule form (Reagila, some countries: Vraylar). Structure and properties Cariprazine (C21H32Cl2N4O, Mr = 427.4 g/mol) is a piperazine and dimethylurea derivative. It is present in the drug as cariprazine hydrochloride, a white powder. Active metabolites … Cariprazine
Products Isavuconazonium sulfate is commercially available as a powder for a concentrate for the preparation of an infusion solution and in capsule form (Cresemba). It was approved in the US and EU in 2015 and in many countries in 2017. Structure and properties Isavuconazonium sulfate (C35H35F2N8O5S+ – HSO4– Mr = 814.8 g/mol) is a prodrug … Isavuconazonium Sulfate
Products Tamoxifen is commercially available in the form of film-coated tablets (Nolvadex, generic). It was synthesized in 1962 and tested as a contraceptive (“morning-after pill”) but was not suitable for this purpose. It was first used as a breast cancer drug in the early 1970s. It has been approved in many countries since 1976. Structure … Tamoxifen (Nolvadex): Drug Effects, Side Effects, Dosage and Uses
Products Tasimelteon was approved in the United States in 2014 and in the EU in 2015 in capsule form (Hetlioz). The drug is not currently registered in many countries. Structure and properties Tasimelteon (C15H19NO2, Mr = 245.3 g/mol) exists as a white crystalline powder that is sparingly soluble in water. It is structurally related to … Tasimelteon
Products Lurasidone is commercially available in the form of film-coated tablets (Latuda). It has been approved in many countries since 2013. In the United States, it was registered as early as 2010. Structure and properties Lurasidone (C28H36N4O2S, Mr = 492.7 g/mol) belongs to the benzoisothiazoles. It exists as a white powder that is sparingly soluble … Lurasidon