Products Estriol is commercially available in many countries as vaginal gel, vaginal cream, vaginal suppositories, vaginal tablets, and tablets for peroral therapy. This article refers to topical use. Structure and properties Estriol (C18H24O3, Mr = 288.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a natural metabolite of … Estriol
Products Velpatasvir was approved in 2016 in fixed combination with the HCV polymerase inhibitor sofosbuvir in film-coated tablet form (Epclusa, Gilead). Another fixed combination is Vosevi with sofosbuvir and voxilaprevir. Structure and properties Velpatasvir (C49H54N8O8, Mr = 883.0 g/mol) Effects Velpatasvir has antiviral properties. The effects are due to binding to the viral protein NS5A … Velpatasvir
Products Doravirin was approved in the US and EU in 2018 and in many countries in 2019 in film-coated tablet form (Pifeltro). It is also combined with lamivudine and tenofovirdisoproxil fixed (Delstrigo). Structure and properties Doravirin (C17H11ClF3N5O3, Mr = 425.8 g/mol) is a pyridinone and triazole derivative that is practically insoluble in water. The drug … Doravirin
