Products Estriol is commercially available in many countries as vaginal gel, vaginal cream, vaginal suppositories, vaginal tablets, and tablets for peroral therapy. This article refers to topical use. Structure and properties Estriol (C18H24O3, Mr = 288.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a natural metabolite of … Estriol
Products Promestrien was commercially available in the form of vaginal capsules and as a vaginal cream (Colpotrophine). It was approved in many countries in 1982 and is now no longer available. Structure and properties Promestriene (C22H32O2, Mr = 328.5 g/mol) is an alkyl derivative of the natural estrogen estradiol. Effects Promestriene (ATC G03CA09) has estrogenic … Promestria
Products Conjugated estrogens have been approved in many countries since 2015 in fixed combination with bazedoxifene (Duavive). Other preparations, such as Premarin and Premella, are off-label in many countries. Other products are available in other countries, such as the United States. Structure and properties Unlike other drugs, conjugated estrogens do not contain a single defined … Conjugated Estrogens
Products Estradiol is commercially available in tablet, transdermal patch, transdermal gel, vaginal ring, and vaginal tablet forms, among others. It is also combined fixed with progestogens. Structure and properties Estradiol (C18H24O2, Mr = Mr = 272.4 g/mol) exists as a white crystalline powder that is practically insoluble in water. Synthetic estradiol is bioidentical with human … Estradiol
Products No finished drug products containing mestranol are commercially available in many countries. Structure and properties Mestranol (C21H26O2, Mr = 310.4 g/mol) is a methoxy derivative and a prodrug of ethinylestradiol. Effects Mestranol has contraceptive properties. Indications For hormonal contraception in combination with a progestin.
Products Tibolone is commercially available in tablet form (Livial, Germany: Liviella). It has been approved in many countries since 1998. Generic versions were registered in 2014. Structure and properties Tibolone (C21H28O2, Mr = 312.4 g/mol) is structurally related to 19-nortestosterone. It carries an ethynyl group like ethynylestradiol. Effects Tibolone (ATC G03CX01) is a prodrug. The … Tibolone
Products Ethinyl estradiol is present in numerous hormonal contraceptives as an estrogenic component in fixed combination with a progestin. In addition to traditional birth control pills, modern dosage forms such as the contraceptive patch and the contraceptive ring are also on the market. Ethinyl estradiol, unlike the female sex hormone estradiol, has a higher oral … Ethinylestradiol
