Insulin Degludec

Products Insulin degludec is commercially available as a solution for injection (Tresiba). It is also combined fixed with insulin aspart (Ryzodeg, see under IDegAsp). It was newly approved in many countries in March 2013. In 2014, a fixed combination with liraglutide was registered (Xultophy); see under IDegLira. Structure and properties Insulin degludec has essentially the … Insulin Degludec

Insulin

Insulin is an endogenous hormone produced in the pancreas. Insulin causes sugar to be absorbed from the blood into the liver and muscles. This causes the blood sugar level to drop. Insulin, also known as insulinum, insulin hormone or islet hormone, can be assigned to the class of proteohormones. All members of this hormone class … Insulin

Insulin Release | Insulin

Insulin Release Insulin is released by various stimuli initiated by the organism. Probably the most important stimulus for the release of the tissue hormone is an increase in the blood sugar level. From a glucose level of approximately 5 mmol/l, the beta cells of the pancreas begin to secrete insulin. In addition, various amino acids, … Insulin Release | Insulin

Insulin associated diseases | Insulin

Insulin associated diseases The metabolic disease known as insulin resistance (synonym: pre-diabetes) is a preliminary stage of type 2 diabetes. It has now been proven that the causes of this disease have a strong genetic component. Studies have shown that 40% of children whose parents have type 2 diabetes suffer from insulin resistance. If two … Insulin associated diseases | Insulin

Indications | Insulin

Indications When is insulin used for therapy? People with type 1 diabetes are dependent on externally supplied insulin because the body’s own insulin production and release is not sufficient. Type 2 diabetics are treated with insulin when dietary measures and oral medications (tablets) no longer have any effect and blood glucose control is unsatisfactory. In … Indications | Insulin

Complications | Insulin

Complications Possible Overdosage of insulin or too little food intake may lead to hypoglycemia. Fat cells can accumulate under the skin at the injection sites and cause hardening. It is possible that the cells become insensitive to insulin because the utilization of glucose in the cell is disturbed or because the interaction between insulin and … Complications | Insulin