How desloratadine works Desloratadine suppresses the effect of histamine (i.e. it is an antihistamine). It belongs to the group of so-called second-generation antihistamines. Histamine is a tissue hormone that not only mediates many physiological processes in the body, but also allergic reactions. The effects triggered by the hormone depend on which of its four binding … Desloratadine: Effect, areas of application, side effects
Definition The dispensing of licensed medicines is strictly regulated by law in many countries. Drugs may be available by prescription (prescription-only), nonprescription, and over-the-counter. Typical dispensing points are pharmacies, drugstores and doctors’ offices, provided that self-dispensing is permitted by the canton. Category E drugs may also be sold in the retail trade, for example in … Dispensing Categories of Medicinal Products
Products Antihistamines are often taken in the form of tablets. In addition, drops, solutions, lozenges, capsules, gels, creams, eye drops, nasal sprays, and injectable solutions are also available, among others. The first active ingredient from this group was phenbenzamine (Antergan), developed in France in the 1940s. It is no longer commercially available today. Structure and … Antihistamines for Allergies
Products The allergy emergency kit is assembled and dispensed individually at a pharmacy or under a doctor’s care. Contents of the allergy emergency kit The following information refers to adults. The composition of the kit is not uniformly regulated and differs between regions and countries. Many countries also use different active ingredients and dosages. Base: … Allergy Emergency Kit
Products Loratadine is commercially available in tablet form (Claritine, Claritine Pollen, generics). It has been approved in many countries since 1991. The active metabolite desloratadine is also available (Aerius, generics). Structure and properties Loratadine (C22H23ClN2O2, Mr = 382.9 g/mol) exists as a white crystalline powder that is practically insoluble in water. It is a prodrug … Loratadine
Products Rupatadine is commercially available in tablet and oral solution forms (Rupafin, Urtimed), among others. The drug has not yet been registered in many countries. Structure and properties Rupatadine (C26H26ClN3, Mr = 415.96 g/mol) is present in drugs as rupatadine fumarate. It is structurally related to loratadine. Rupatadine is also partially metabolized to desloratadine but … Rupatadine
Products Desloratadine is commercially available as 5 mg film-coated tablets and as a solution (Aerius, generics). It has been approved in many countries since 2001. The syrup was replaced in 2011 by a solution that is sugar- and dye-free. The concentration remains identical (0.5 mg/ml). The fixed combination with pseudoephedrine is not yet available in … Desloratadine
