GnRH Analogs

Products GnRH analogs are commercially available in many countries in the form of injectables, implants, and nasal sprays, among others. The first agent to be approved was goserelin (Zoladex) in 1990. Structure and properties GnRH analogs are synthetically produced derivatives of gonadotropin-releasing hormone (GnRH, LHRH) produced in the hypothalamus. GnRH is a decapeptide and has … GnRH Analogs

Deslorelin

Products Deslorelin is commercially available as an implant for animals (Suprelorin). It has been approved in many countries since 2009. Structure and properties Deslorelin is an analog of GnRH. Effects Deslorelin (ATCvet QH01CA93) inhibits the formation and secretion of FSH and LH. Indications Achieving temporary infertility in healthy, nonneutered, sexually mature male dogs.