Effects ADH analogs (ATC H01BA) are derivatives of the antidiuretic hormone ADH (= vasopressin), which has antidiuretic and vasoconstrictor properties. The vasopressin analogs are modified to be predominantly antidiuretic or predominantly vasoconstrictor. Indications Diabetes insipidus Enuresis nocturna (bedwetting) Polyuria, polydipsia after hypophysectomy. Acute esophageal variceal bleeding (Terlipressin). Agents Desmopressin Terlipressin
Products Nasal sprays are very widely used and there are many different products on the market, which are approved drugs or medical devices (see below). Nasal sprays are also manufactured in pharmacies. Structure and properties Nasal sprays are solutions, emulsions, or suspensions intended for spraying into the nasal cavities. They may contain one or more … Nasal Sprays
Products Vonicog alfa was approved in the United States in 2015 and in the EU and Switzerland in 2018 as a lyophilizate and solvent for the preparation of a solution for injection (Veyvondi, USA: Vonvendi). It was the first recombinant von Willebrand factor. Structure and properties Vonicog alfa is a purified, recombinant, human von Willebrand … Vonicog Alfa
Symptoms In enuresis nocturna, a child older than 5 years empties the bladder repeatedly at night without an organic or medical cause. It does not wake up when the bladder is full and therefore cannot go to the toilet. During the day, on the other hand, everything works normally. The problem is slightly more common … Bedwetting (Enuresis Nocturna)
Products Desmopressin is commercially available as a solution for injection, in the form of nasal drops, as a nasal spray, tablets, and sublingual tablets (e.g., Minirin, Nocutil, other drugs). It has been approved in many countries since 1973. Structure and properties Desmopressin (C48H68N14O14S2, Mr = 1129.3 g/mol) is present in the drugs as desmopressin acetate, … Desmopressin
Introduction Nasal sprays belong to the group of so-called aerosols, i.e. mixtures of liquid components and gas. Through the spray system, the liquid active ingredients are finely distributed in the air and can be inhaled. In principle, a distinction is made between locally acting and systemically acting nasal sprays. However, the term ‘nasal spray’ usually … Nasal Spray
Glucocorticoid Nasal Spray Glucocorticoid nasal spray, popularly known as “cortisone nasal spray“, has an anti-allergic and anti-inflammatory effect on the nasal mucosa. The treatment can alleviate symptoms of allergic hay fever, but also of colds.In contrast to antihistamine nasal spray, cortisone products have to be used for longer, but the effect achieved is stronger. If … Glucocorticoid Nasal Spray | Nasal Spray
Systemic nasal sprays Systemic nasal sprays do not act locally in the nose, but are effective throughout the body. The nasal mucous membrane is very well supplied with blood, and is therefore ideally suited for the absorption of certain active ingredients into the body’s circulation. For example, in contrast to oral administration, the gastrointestinal tract … Systemic nasal sprays | Nasal Spray
Symptoms Urinary incontinence manifests as involuntary leakage of urine. The common problem poses a psychosocial challenge for those affected, which can lead to changes in personal activities and a loss of quality of life. Risk factors include female gender, age, obesity, and numerous medical conditions. Causes Urinary incontinence can occur as a result of pathologic, … Urinary Incontinence: Causes and Treatment
