Diclofenac: Effects, Dosage, Side Effects

Pain and inflammation – a typical field of application for the active ingredient Diclofenac. Therefore, Diclofenac helps especially in chronic joint diseases such as rheumatism or sports injuries such as strains and bruises. Compared with acetylsalicylic acid and paracetamol, the active ingredient diclofenac is one of the rather younger drugs: diclofenac has been on the … Diclofenac: Effects, Dosage, Side Effects

Painkiller Abuse

Anyone who regularly reaches for painkillers is not only fighting pain, but may even be causing it themselves. “Long-term use can lead to pain triggered by the painkiller,” warns Dr. Isabel Justus, managing director of the Bremen Chamber of Pharmacists. A permanent pain therapy in the self-course can also cause life-threatening health damage. Pain pills: … Painkiller Abuse

First-Pass Metabolism

The effect of the first liver passage For a perorally administered pharmaceutical agent to exert its effects at the site of action, it usually must enter the systemic circulation. To do so, it must pass through the intestinal wall, the liver, and part of the circulatory system. Despite complete absorption in the intestine, the bioavailability … First-Pass Metabolism

Antipyretics

Products Antipyretics are available in numerous dosage forms. These include, for example, tablets, effervescent tablets, suppositories, juices, and chewable tablets. The name is derived from the technical term pyrexia (fever). The first synthetic agents, such as acetanilide, salicylic acid, and acetylsalicylic acid, were developed in the 19th century. Structure and properties Antipyretics do not have … Antipyretics

Lithium Therapy: Treatment, Effects & Risks

Lithium therapy is used for affective disorders and treatment-resistant schizophrenia. Lithium causes mood stabilization and is the only known drug that has been shown to have a suicide-preventive effect. What is lithium therapy? Lithium therapy, used in psychiatry, involves administering lithium to stabilize mood. The use of lithium as a drug in the context of … Lithium Therapy: Treatment, Effects & Risks

Sunburn Causes and Remedies

Symptoms Sunburn manifests itself as an extensive reddening of the skin (erythema), as a 1st degree burn with pain, burning, itching, tightening of the skin and, in severe cases, additionally with skin blisters (transition to a 2nd degree burn). It develops continuously over several hours and reaches a maximum after 12 to 24 hours. The … Sunburn Causes and Remedies

Tension Headache

Symptoms Sporadic, frequent, or chronic in onset: A bilateral pain originating in the forehead and extending along the sides of the head to the occipital bone at the back of the skull Pain quality: pulling, pressing, constricting, non-pulsating. Duration between 30 minutes and 7 days Mild to moderate pain, normal daily activities are possible Radiation … Tension Headache

Bruise (Hematoma) Symptoms and Causes

Symptoms Possible symptoms of a bruise (technical term: hematoma) include swelling, pain, inflammation, and discoloration of the skin that changes (red, blue, purple, green, yellow, brown) during the healing process. This text refers to simple and small-surface complaints that can be considered for self-medication. Causes The cause of a hematoma is blood leaking from injured … Bruise (Hematoma) Symptoms and Causes

Nalmefene

Products Nalmefene is commercially available in the form of film-coated tablets (Selincro). It was registered in many countries in 2014. Structure and properties Nalmefene (C21H25NO3, Mr = 339.4 g/mol) is structurally closely related to naltrexone, from which it is derived. In the drug product, it is present as nalmefene hydrochloride and dihydrate, a white crystalline … Nalmefene

Soft Capsules

Products Various drugs and dietary supplements are commercially available in the form of soft capsules. Active ingredients administered with this dosage form include, for example, pain relievers (e.g., diclofenac, ibuprofen, acetaminophen), retinoids such as isotretinoin, thyroid hormones, cytostatics, ginseng, vitamins, and fatty oils such as fish oil, krill oil, linseed oil, and wheat germ oil. … Soft Capsules

Gout Causes and Treatment

Symptoms Gout is an inflammatory disease of the joints that manifests acutely in attacks of severe pain that worsens with pressure, touch, and movement. The joints are swollen with inflammation, and the skin is red and warm. Fever is observed. Gout often begins in the lower extremities and at the metatarsophalangeal joint (podagra). Urat crystals … Gout Causes and Treatment

Agranulocytosis Symptoms and Treatment

Symptoms Typical symptoms of agranulocytosis include fever, chills, feeling ill, tonsillitis, sore throat, difficulty swallowing, and lesions and bleeding of the oral, nasal, pharyngeal, genital, or anal mucosa. The disease can lead to dangerous infections and blood poisoning and, if left untreated, can relatively often be fatal. Agranulocytosis usually occurs rarely to very rarely as … Agranulocytosis Symptoms and Treatment