Castor Oil: Medicinal Uses

Products Castor oil is available in pharmacies and drugstores as an open product. Specialty retailers can order it from Hänseler, for example. Extraction Virgin castor oil is the fatty oil obtained from the seeds of the miracle tree L. of the spurge family by cold pressing. A suitable antioxidant may be added. Refined castor oil … Castor Oil: Medicinal Uses

Diacerein

Products Diacerein is not approved in many countries. In Austria, it is commercially available in capsule form (Verboril, Artrolyt). Structure and properties Diacerein (C19H12O8, Mr = 368.3 g/mol) is a diacetylated rhein and is therefore also known as diacetylrhein. It is a prodrug and is rapidly metabolized in the body to its active metabolite rhein. … Diacerein

Digoxin

Synonyms cardiac glycosides Drugs Cardiac arrhythmia Digitoxin Digoxin is an active ingredient that belongs to the group of cardiac glycosides. Among other things, it improves the efficiency of the heart and is therefore prescribed, for example, in cases of heart failure (cardiac insufficiency). Origin Digoxin and digitoxin can be extracted from the same plant: The … Digoxin

Indications | Digoxin

Indications Digoxin is used for the following indications: Heart failure (pumping weakness of the heart) Atrial flutter and flicker (due to the delay in excitation transfer) Side effects Digoxin has a narrow therapeutic range. This means that it is very easy to overdose, which leads to intoxication. This is because inhibition of the sodium–potassium pump … Indications | Digoxin

Lansoprazole

Products Lansoprazole is commercially available in the form of capsules as meltable tablets (Agopton, generics). It has been approved in many countries since 1993. Structure and properties Lansoprazole (C16H14F3N3O2S, Mr = 369.4 g/mol) is a benzimidazole and pyridine derivative. It exists as a white to brownish-white, odorless, crystalline powder that is practically insoluble in water. … Lansoprazole

Sitagliptin

Products Sitagliptin is commercially available in film-coated tablet form as a monopreparation (Januvia) and as a fixed combination with metformin (Janumet, Janumet XR). It was approved in many countries in 2007 as the first representative of the gliptins. The combination with simvastatin is not yet registered in many countries (Juvisync). Generics were approved in 2018. … Sitagliptin

Pramipexole

Products Pramipexole is commercially available in tablet and sustained-release tablet form (Sifrol, Sifrol ER, generics). It has been approved in many countries since 1997; generics were released in 2010 and entered the market in January 2011. Sifrol ER sustained-release tablets were relaunched by the original manufacturer in 2010. Structure and properties Pramipexole (C10H17N3S, Mr = … Pramipexole

Flibanserin

Products Flibanserin (Addyi) was approved in the United States in 2015 in the form of film-coated tablets. The drug has not yet been registered in many countries. Flibanserin was originally developed at Boehringer Ingelheim as an antidepressant. It was marketed in the United States by Sprout Pharmaceuticals. Structure and properties Flibanserin (C20H21F3N4O, Mr = 390.4 … Flibanserin

P-Glycoprotein

P-glycoprotein P-glycoprotein (P-gp, MDR1) is a primary active efflux transporter with a molecular weight of 170 kDa, belonging to the ABC superfamily and consisting of 1280 amino acids. P-gp is the product of the -gene (formerly: ). P is for , ABC is for . Occurrence P-glycoprotein is found on various tissues of the human … P-Glycoprotein

Cardiac catheter examination

Coronary angiography A cardiac catheter examination is a diagnostic or therapeutic measure to detect and correct cardiovascular changes with the help of a catheter inserted into the vascular system. A cardiac catheter is a very thin, internally hollow instrument several meters long, with a guide wire in its central cavity. This guidewire serves to guide … Cardiac catheter examination