Products Saxagliptin is commercially available in the form of film-coated tablets (Onglyza). It was approved in many countries after sitagliptin (Januvia) and vildagliptin (Galvus) as the 3rd active ingredient from the gliptins group in February 2010. Since 2012, two additional combination products with metformin have been registered (Duoglyze, Kombiglyze XR). Kombiglyze XR entered the market … Saxagliptin
Products Vildagliptin is commercially available in tablet form as a monopreparation (Galvus) and in fixed combination with metformin (Galvumet). It has been approved in the EU since 2007 and in many countries since 2008. Generic versions were registered in 2020. Structure and properties Vildagliptin (C17H25N3O2, Mr = 303.40 g/mol) is a hydroxy-adamantane, a carbonitrile and … Vildagliptin
Products Sitagliptin is commercially available in film-coated tablet form as a monopreparation (Januvia) and as a fixed combination with metformin (Janumet, Janumet XR). It was approved in many countries in 2007 as the first representative of the gliptins. The combination with simvastatin is not yet registered in many countries (Juvisync). Generics were approved in 2018. … Sitagliptin
