Acamprosate

Products Acamprosate is commercially available in the form of enteric-coated film-coated tablets (Campral). The active ingredient has been approved in many countries since 1995. Structure and properties Acamprosate (C5H11NO4S, Mr =181.2 g/mol) is present in drugs as acamprosate calcium, a white powder that is readily soluble in water. It has structural similarities to the neurotransmitter … Acamprosate

Insecticides

Effects Insecticidal Antiparasitic Ovicidal: killing eggs Larvicidal: larvae killing Partially insect repellent Indications Infestation by parasites, such as head lice and fleas. Active ingredients (selection) Allethrin Crotamiton (Eurax, out of trade). Disulfiram (Antabus, not commercially available for this indication). Flea medication Ivermectin (Stromectol, France) Lindane (Jacutin, out of trade). Malathion (Prioderm, out of trade) Mesulfen … Insecticides

Metal Allergy

Symptoms Local skin reactions such as itching, inflammation, redness, and blistering occur acutely, especially at the sites of contact with the trigger. In the chronic stage, dry, scaly and cracked skin is often observed, e.g. in the form of chronic hand eczema. Affected areas include the hands, abdomen and earlobes. The rash can also appear … Metal Allergy

Bad Breath

Symptoms Bad breath manifests itself in foul-smelling breath. The bad odor is also a psychosocial problem and can lower self-esteem, lead to feelings of shame, and make it difficult to communicate with others. Causes True, chronic bad breath originates from the oral cavity and mainly from the coating on the tongue in over 80 to … Bad Breath

Ethambutol

Products Ethambutol is commercially available in the form of film-coated tablets (Myambutol, combination products). It has been approved in many countries since 1967. Structure and properties Ethambutol (C10H24N2O2, Mr = 204.3 g/mol) is present in drugs as ethambutol dihydrochloride, a white, crystalline, hygroscopic powder that is readily soluble in water. Effects Ethambutol (ATC J04AK02) has … Ethambutol

Ethanol

Products Alcohol is contained in numerous intoxicating and stimulant products, such as wines, sparkling wines, beers and high-proof spirits. Per capita consumption in many countries averages about 8 liters of pure alcohol per year. Ethanol is also available as an open product in various qualities in pharmacies and drugstores (e.g. ethanol 70% with camphor, ethanol … Ethanol

Isoniazid

Products Isoniazid is commercially available in tablet form (eg, Isoniazid Labatec, combination products). Structure and properties Isoniazid (C6H7N3O, Mr = 137.1 g/mol) exists as a white crystalline powder or colorless crystals and is readily soluble in water. It is also known as isonicotinylhydrazine (INH). Effects Isoniazid (ATC J04AC01) has bacteriostatic to bactericidal properties against . … Isoniazid

Interactions

Definition When two or more drugs are combined, they may affect each other. This is especially true with regard to their pharmacokinetics (ADME) and effects and adverse effects (pharmacodynamics). This phenomenon is called interaction and drug-drug interaction. Interactions are usually undesirable because they can lead to, for example, loss of efficacy, side effects, poisoning, hospitalization, … Interactions

Disulfiram

Products Disulfiram is commercially available in the form of water-suspendable tablets called dispersible tablets (Antabus). It has been approved in many countries since 1949. Structure and properties Disulfiram or tetraethylthiuram disulfide (C10H20N2S4, Mr = 296.54 g/mol) is a white to almost white crystalline powder that is practically insoluble in water. Prior to its medical use, … Disulfiram

Phenazone

Products Phenazone is currently marketed in many countries exclusively in the form of ear drops. Tablets have not been available since the “group analgesics review” conducted by the Medicines Agency. This is in contrast to other countries. This article refers to oral therapy. Phenazone is one of the first synthetically produced analgesics and antipyretics. It … Phenazone

Prodrugs

What are prodrugs? Not all active pharmaceutical ingredients are directly active. Some must first be converted to the active substance by an enzymatic or non-enzymatic conversion step in the body. These are the so-called . The term was introduced by Adrien Albert in 1958. It is estimated that up to 10% of all active ingredients … Prodrugs

Dispersible Tablets

Definition and properties Dispersible tablets are uncoated tablets or film-coated tablets that can be suspended or dissolved in water before ingestion. They are designated by the Pharmacopoeia as “tablets for the preparation of a suspension for ingestion” and “tablets for the preparation of a solution for ingestion.” When dissolved, a homogeneous suspension or solution is … Dispersible Tablets